Papaverine, 40 mg tablets 10 pcs

Papaverine is a myotropic antispasmodic (relieves smooth muscle spasms) drug.

Limits the tone and reduces the contractile activity of smooth muscles and therefore has a vasodilator and antispasmodic (relieves spasms) effect.

In high doses, it reduces excitability of the heart muscle and slows intracardiac conduction.

Indications

• Spasms (severe narrowing of the lumen) of the blood vessels of the brain,
• sthenocardia,
• endarteritis (inflammation of the inner lining of the arteries,
• cholecystitis (inflammation of the gallbladder),
• pylorospasm (spasm of the stomach’s gateway muscles),
• spastic colitis,
• spasm of the urinary tract,
• bronchospasm (narrowing of the lumen of the bronchi).

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Active ingredient

Papaverine

Composition

Composition per tablet:

Papaverine hydrochloride – 40 mg

Excipients:

Potato starch – 149.8 mg,

Stearic acid – 2.7 mg,

Saccharose (granulated sugar) – 157.5 mg.

How to take, the dosage

Inside. Adults take 40-60 mg 3-4 times a day. The highest single dose is 200 mg, the daily dose is 600 mg. Children over 10 years of age take 20 mg 3-4 times a day. Children under 10 years of age are recommended to take the child form of the drug.

Interaction

Papaverine reduces the antiparkinsonian effect of levodopa and the hypotensive effect of methadone.

In combination with barbiturates the antispasmodic effect of papaverine is increased.

When combined with tricyclic antidepressants procainamide reserpine quinidine, the hypotensive effect of papaverine may be increased.

Special Instructions

The administration of ethanol should be avoided during treatment.

The vasodilating effect of Papaverine is reduced by tobacco smoking.

When prescribing Papaverine to patients with diabetes mellitus it should be noted that the tablet contains sucrose as excipients.

Contraindications

– hypersensitivity to papaverine and other drug components;
– atrioventricular blockade;
– glaucoma;
– severe renal insufficiency;
– Sucrose/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption;
– respiratory depression, coma;
– senile age (risk of hyperthermia);
– children under 10 years (for this dosage form).

With caution
– conditions after craniocerebral injury;
– impairment of renal function;
– insufficiency of adrenal function;
– Hypothyroidism;
– prostatic hyperplasia;
– supraventricular tachycardia;
– shock conditions;
– pregnancy, lactation (see Section “Administration during pregnancy and lactation”).
– pregnancy and lactation (see section “Administration during pregnancy and lactation”).

Side effects

Allergic reactions atrioventricular block ventricular extrasystole decrease in blood pressure constipation somnolence increase in the activity of “liver” transaminases eosinophilia.