Hydrocortisone-Pos, eye ointment 1% 2.5g

Pharmacotherapeutic group – glucocorticosteroid for topical use.
TACH Code S01BA02

Pharmacodynamics

The drug contains as active ingredient hydrocortisone acetate – glucocorticosteroid.

When used topically, hydrocortisone acetate suppresses inflammatory and allergic reactions occurring in the outer membranes and anterior segment of the eye.

The action of hydrocortisone acetate, like other corticosteroids, is based on suppression of leukocyte and tissue macrophage function. It restricts migration of leukocytes, macrophages and mast cells to the area of inflammation and inhibits formation of interleukin-1. It promotes stabilization of lysosomal membranes, thus reducing the concentration of pro-theolytic enzymes in the area of inflammation. Reduces capillary permeability caused by histamine release. Inhibits fibroblast activity and collagen formation. It inhibits the activity of phospholipase A2 which leads to the suppression of prostaglandin and leukotrienes synthesis.

Pharmacokinetics

Possible penetration of hydrocortisone acetate through the cornea into the moisture of the anterior chamber of the eye due to its lipophilic properties. Penetration of hydrocortisone acetate into the tissues depends on the condition of the cornea and increases significantly in case of inflammation or damage to the ocular mucosa.

Indications

• Allergic conjunctivitis, blepharitis, blepharoconjunctivitis;
• Acute and chronic iritis, iridocyclitis;
• Allergic conjunctivitis.
• Inflammatory phenomena after eyeball surgery
• Keating neovascularization after treated keratitis, chemical burns.

Active ingredient

Hydrocortisone

Composition

1 g of Hydrocortisone-POS 1% eye ointment contains:

Active ingredient: hydrocortisone acetate 10.0 mg

Excipients: petroleum jelly, liquid paraffin, lanolin.

How to take, the dosage

In the absence of other recommendations from your physician, follow these instructions for use of Hydrocortisone-POS Eye Ointment 1%, 2.5% exactly.

A 1 cm long strip of ointment is applied 2-3 times a day behind the lower eyelid. Open the tube, tilt your head slightly backwards and place a 1 cm strip of ointment behind the lower eyelid. Gently close your eyes.

Close the tube tightly after use. Avoid contact of the tube with the skin or conjunctiva surface during application of the eye ointment.

If multiple eye medications are used at the same time, it is recommended that Hydrocortisone-POS Eye Ointment 1%, 2.5% be applied no earlier than 15 minutes after using the eye drops.

The duration of treatment with Hydrocortisone-POS Eye Ointment 1%, 2.5% usually does not exceed 2 to 3 weeks.

Interaction

Concomitant use of Hydrocortisone-POS Eye Ointment 1%, 2.5% and other agents that may cause an increase in intraocular pressure (e.g., atropine and other cholinergic agents) may contribute to an additional increase in intraocular pressure, especially in predisposed patients.

Special Instructions

Do not wear contact lenses during treatment with Hydrocortisone-POS Eye Ointment 1%, 2.5%. Immediately after using Hydrocortisone-POS Eye Ointment 1%, 2.5% a short-term visual acuity disorder may occur, resulting in delayed mental and physical reactions. Therefore, it is not recommended to use the drug immediately before operating machinery and driving motor transport.

Synopsis

White with yellowish tinge homogeneous suspension ointment.

Contraindications

• Hypersensitivity to any component of the drug;
• Subsurface corneal herpes and other viral diseases of the eye;
• Indications of corneal epithelium and corneal lesions;
• Tuberculosis, bacterial or fungal infections of the eyeCorneal epithelial integrity disorders and corneal damage;
• Tuberculosis, bacterial or fungal eye infections;
• Trachoma;
• Vaccination period.

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Side effects

If you experience a side effect during treatment with Hydrocortisone-POS Eye Ointment 1%, 2.5% that is not described in this leaflet or if you are unsure of the effectiveness of the product, please inform your doctor or pharmacist.
In very rare cases, allergic reactions such as burning, scleral injection, contact dermatitis, dermatoconjunctivitis, eyelid eczema may occur.

Long-term use of the drug may cause secondary glaucoma and complicated cataracts, therefore it is recommended to monitor the intraocular pressure regularly if the drug is used for more than 2 weeks and in patients with a history of glaucoma.

If any side effects occur, discontinue use and see the attending physician (ophthalmologist) as soon as possible.

Overdose

No symptoms of overdose have been reported when used topically at the recommended dose.

Pregnancy use

To date, there are no clinical trial data on the use of Hydrocortisone-POS 1%, 2.5% Eye Ointment during pregnancy, lactation and in children. It is possible to use Hydrocortisone-POS 1%, 2.5% ointment eye for children over 1 year old, pregnant and nursing mothers by prescription of a doctor if the expected medical effect exceeds the risk of possible side effects. Duration of drug administration in this category of patients should not exceed 7-10 days.

Similarities

Locoid, Laticort, Hydrocortisone, Cortef, Locoid Lipokrem, Hydrocortisone ointment