🐾 Dechinel Plus anthelmintic tablets for dogs of large breeds, 60 pcs.

Dechinel Plus, due to its active ingredients, has antiparasitic activity against cestodes: Echinococcus granulosus, Echinococcus multilocularis, Mesocestoides lineatus, Diphyllobothrium latum, Dipylidium caninum, Multiceps multiceps, Taenia spp. and nematodes: Toxocara canis, Toxascaris leonina, Uncinaria spp, Ancylostoma spp., Trichuris vulpis. Febantel, moderately absorbed from the gastrointestinal tract, causes inhibition of tubulin protein synthesis and glucose entry process in nematodes, simultaneously inhibiting fumaratreductase – enzyme responsible for energy metabolism of helminthes. Pirantel Embonate is very poorly absorbed by oral administration and therefore, has its effect directly on the surface of the mucous membrane of the gastrointestinal tract of the sick dog. It blocks nematode neuromuscular impulse transmission and causes paralysis of helminth muscles, so parasites are easily eliminated from the gastrointestinal tract of the host. Praziquantel is well absorbed in the gastrointestinal tract and has devastating effect on cestodes (tapeworms) due to increased permeability of parasite cell membranes for calcium ions and inhibition of fumaratreductase, which causes spastic contraction of parasite muscles, turning into paralysis. Praziquantel is excreted with bile unchanged. Dechinel Plus in terms of its effect on the body of warm-blooded animals refers to low-hazardous substances and in recommended doses has no sensitizing and hepatotoxic effect.

Indications

Helminthiasis

Active ingredient

Febantel, pyrantel, praziquantel

Composition

Anthelminthic drug for dogs Dechinel Plus (international nonproprietary name: febantel + pyrantel embonate + praziquantel) as active substances in one tablet contains: 525 mg of febantel, 504 mg of pyrantel embonate and 175 mg of praziquantel, and as excipients – lactose monohydrate, corn starch, povidone K30, sodium lauryl sulfate, microcrystalline cellulose, colloidal silicon anhydride and magnesium stearate

How to take, the dosage

Dechinel Plus is administered to dogs individually orally, once in the morning feeding at the rate of 1 tablet per 35 kg of animal weight.
Before using the drug starvation diet and use of laxatives is not required. In cases of intensive helminth infestation it is recommended to apply the preparation in 14 days in the same dose. The drug is administered to animals with therapeutic purpose according to indications, and with preventive purpose – quarterly (once every 3 months) in a therapeutic dose.
Symptoms of overdose in dogs were not found.
No special effects of the drug during its first use.

Contraindications

Increased individual sensitivity to the drug components. Do not use the drug in puppies in the first three weeks of life and puppy bitches in the first two-thirds of pregnancy.
Do not prescribe Dechinel Plus simultaneously with piperazine derivatives, levamisole, organophosphorus compounds and other drugs with cholinergic effect.

Side effects

As a rule, no side effects and complications are observed when using Dechinel Plus in accordance with these instructions.
Individual signs of intolerance of the drug components in sensitive animals are possible in rare cases. In case of allergic reactions the use of Dechinel Plus is stopped and desensitization therapy is carried out.