Nasivin, spray 0.05% 10 ml

Nasivin is an alpha-adrenomimetic, vasoconstrictor.

As an imidazoline derivative, at low concentrations it has mainly α2-adrenomimetic effect, at high concentrations it also acts on α1-adrenoreceptors.

It narrows blood vessels at the application site, reduces swelling of the nasal mucosa and the upper respiratory tract. When applied locally nasally in therapeutic concentrations it does not irritate the mucosa and does not cause hyperemia.

Studies of radioactive isotope-labeled oxymetazoline have shown that this rhinological agent administered through the nose has no systemic action.

Indications

Sinusitis, Runny nose (rhinitis), Pollinosis, Otitis media, Allergic rhinitis, Flu, Nasal congestion, Colds

• Acute respiratory diseases with rhinitis
• Acute allergic rhinitis
• Rhinitis.
• Acute exacerbation of oedema in sinusitis, eustachitis, otitis media
• To relieve nasal sinus oedema before diagnostic manipulations of the nasal passages.

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Active ingredient

Oxymetazoline

Composition

1 ml contains:

Oxymetazoline hydrochloride 0.5 mg.

How to take, the dosage

Adults and children over 6 years of age – 1 injection into each nasal passage 2-3 times a day.

The drug is used for 3-5 days.

Special Instructions

Prolonged use of anti-inflammatory nasal decongestants may weaken their effect.

The abuse of these products may cause mucosal atrophy and reactive hyperemia with medicated rhinitis, as well as mucosal epithelial damage and inhibition of epithelial activity.

Long-term use and overdose should be avoided.

Contraindications

• Hypersensitivity;

• Atrophic rhinitis;

• Closed angle glaucoma.

• Age under 1 year – for Nazivin® 0.025 and 0.05%;

• Age under 6 years – for Nazivin® 0.05%.

Side effects

Sometimes – burning or dry nasal mucosa, sneezing;

Seldom – a strong feeling of “stuffy” nose (reactive hyperemia);

Sometimesvery rarely – anxiety, insomnia, fatigue, headache, nausea.

Multiple overdoses with topical nasal use sometimes result in systemic sympathomimetic effects such as increased heart rate (tachycardia) and increased BP.

Overdose

Symptoms (after significant overdose or accidental ingestion):

Pupil constriction, nausea, vomiting, cyanosis, elevated body temperature, tachycardia, arrhythmia, vascular failure, arterial hypertension, respiratory distress, pulmonary edema, cardiac arrest; In addition, mental disorders may appear, as well as depression of CNS functions, accompanied by drowsiness, decreased body temperature, bradycardia, arterial hypotension, respiratory arrest and possible development of coma.

Treatment:

Gastric lavage, administration of activated charcoal and immediate medical attention.

Similarities

Afrin, Nasivin, Nasol, Otrivin, Nasol Advance, Nasivin Sensitive, Rinostop, Nesopin, Oxyfrine, Sialor, Rinostop Extra, Cold and Flu, No Time to Be Sick