Nasivin® (oxymetazoline) has a vasoconstrictor effect. When applied topically on inflamed nasal mucosa it reduces nasal swelling and nasal discharge. It restores nasal breathing.
Indications
Pollinosis, runny nose (rhinitis), stuffy nose, otitis media, allergic rhinitis, colds, sinusitis, flu
- treatment of acute respiratory diseases accompanied by a runny nose;
- allergic rhinitis;
- allergic rhinitis.rhinitis vasomotor;
- to restore drainage in case of inflammation of paranasal sinuses, eustachitis, otitis media;
- to eliminate edema before diagnostic manipulations of the nasal passages.
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Active ingredient
Oxymetazoline
Composition
1 ml of the drug contains:
Active ingredient:
Nasivin 0.01% – Oxymetazoline hydrochloride 0.1 mg
Nasivin 0.025% – Oxymetazoline hydrochloride 0.25 mg
Excipients:
benzalkonium chloride 50% solution,
dimethate dihydrate,
sodium dihydrophosphate dihydrate,
How to take, the dosage
Nasivin® 0,01 %, 0,025 % and 0,05 % drops are intended for application in the nose.
Adults and children over 6 years old: apply Nasivin® 0,05 % drops 1 – 2 drops in each nostril 2 – 3 times a day.
Children from 1 year to 6 years of age: apply 1 – 2 drops of Nazivin® 0,025 % drops into each nostril 2 – 3 times a day.
Children under 1 year of age: children under 4 weeks of age are prescribed 1 drop of Nazivin® 0,01 % into each nostril 2 – 3 times a day. From the 5th week of life and up to 1 year of age – 1 to 2 drops in each nostril 2 to 3 times a day. To ensure accurate dosage, a bottle of Nazivin® 0.01% drops has a graduated dropper with markings of the number of drops. For example, if 1 drop is prescribed, the pipette should be filled with the solution to the mark 1. The following procedure has also been proven to be effective: Depending on age 1 – 2 drops of 0.01 % solution are put on absorbent cotton and wiped nasal passages.
Nasivin® 0.01 %, 0.025 % and 0.05 % drops should be used for 3 – 5 days. Doses higher than recommended can be used only under the supervision of a doctor.
Interaction
When concomitant administration of MAOI blockers and tricyclic antidepressants – increase in blood pressure. Co-prescription of other vasoconstrictors increases the risk of side effects.
Special Instructions
Long-term use and overdose of the drug should be avoided, especially in children.
After long-term use or administration of rhinitis remedies containing oxymetazoline, in doses higher than recommended, the overall effect on the cardiovascular system and the central nervous system cannot be excluded.
Contraindications
Atrophic rhinitis; closed-angle glaucoma; hypersensitivity to the drug components. The recommended concentrations of the drug for different age categories should be adhered to (see routes of administration).
With caution
In patients taking monoamine oxidase inhibitors and other drugs that contribute to increased blood pressure for up to 10 days after their use; In patients with elevated intraocular pressure, during pregnancy and lactation, in severe forms of cardiovascular disease (hypertension, angina pectoris); in thyrotoxicosis and diabetes.
Side effects
Sometimes: burning or dry nasal membranes, sneezing.
In rare cases: after the effect of using Nazivin® passes, a strong feeling of “stuffy” nose (reactive hyperemia). Repeated overdose with topical nasal use sometimes leads to systemic sympathomimetic effects such as increased pulse rate (tachycardia) and increased blood pressure.
In very rare cases, anxiety, insomnia, fatigue, headaches and nausea have been observed.
Prolonged continuous use of vasoconstrictors may lead to tachyphylaxis, nasal mucosal atrophy and recurrent nasal mucosal edema (medication-induced rhinitis).
Overdose
Symptoms (after significant overdose or accidental ingestion): constriction of pupils, nausea, vomiting, cyanosis, increased body temperature, tachycardia, arrhythmia, vascular failure, arterial hypertension, respiratory distress, pulmonary edema, cardiac arrest; also, mental disorders may appear, as well as CNS depression accompanied by drowsiness, lower body temperature, bradycardia, arterial hypotension, respiratory arrest and possible development of coma.
Treatment: gastric lavage, administration of activated charcoal and immediate medical attention.
Pregnancy use
When using during pregnancy or breastfeeding do not exceed the recommended dosage.
Similarities
Afrin, Nasivin, Nasol, Otrivin, Nasol Advance, Nasivin Sensitive, Rinostop, Nesopin, Oxyfrine, Sialor, Rinostop Extra, Cold and Flu, No Time to Be Sick
Weight | 0.033 kg |
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Shelf life | 3 years |
Conditions of storage | In a light-protected place at a temperature not exceeding 25 °C. |
Manufacturer | Sofarimex Industria Quimica e Pharmasuetica S.A., Portugal |
Medication form | nasal drops |
Brand | Sofarimex Industria Quimica e Pharmasuetica S.A. |
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