Vibrocil, spray 15 ml
€13.13 €10.94
Pharmacotherapeutic group: Antinoconstrictive drug
ATX code. R01AB01
Pharmacological properties: Vibrocil is a combination drug containing phenylephrine and dimethindene.
Phenylephrine is a sympathomimetic agent, when used topically it has a moderate vasoconstrictor effect (due to stimulation of alpha1-adrenoreceptors located in the venous vessels of the nasal mucosa), it eliminates swelling of the nasal mucosa and its accessory sinuses.
Dimetinden is an anti-allergic agent – an antagonist of histamine H1-receptors; it does not reduce activity of the nasal mucosal epithelium.
Pharmacokinetics. Vibrocil is intended for topical use and its activity is independent of the concentration of active substances in blood plasma.
Indications
Acute rhinitis (including runny nose with colds); allergic rhinitis (including hay fever); vasomotor rhinitis; chronic rhinitis; acute and chronic sinusitis; acute otitis media (as adjuvant treatment). Preparation for surgical interventions in the nasal area and elimination of edema of nasal mucosa and sinuses after surgical interventions in this area.
Active ingredient
Dimethinden, Phenylephrine
Composition
Active ingredients:
Phenylephrine 2.5 mg;
Dimethindene maleate 250 µg.
Auxiliary substances:
Benzalkonium chloride 50% solution (in terms of benzalkonium chloride) – 0.2 mg (0.1 mg);
Citric acid monohydrate – 2.6 mg;
Sodium hydrophosphate – 4.4 mg;
Sorbitol – 35 mg;
Lavender oil – 0.2 mg;
Water – up to 1 ml.
How to take, the dosage
Children over 6 years of age and adults are prescribed 1-2 sprays in each nostril 3-4 times a day. When using the spray, the sprayer should be held vertically with the tip upwards. Holding the head straight, insert the tip into the nasal passage, once a short sharp movement squeeze the spray, and taking the tip out of the nose, unclench. During the injection it is recommended to inhale slightly through the nose. The nasal passages should be thoroughly cleaned before the drug is injected.
Special Instructions
Vibrocil in gel form is especially indicated in cases of dry nasal mucosa, in the presence of crusts, in the effects of nasal trauma, as well as to prevent nasal congestion at night.
Vibrocil should not be used for more than 1 week without consulting a doctor. Prolonged (more than 2 weeks) or excessive use of the drug may cause tachyphylaxis, and the “ricochet” effect (drug-induced rhinitis), lead to the development of systemic vasoconstrictor action.
Do not exceed the recommended doses of Vibrocil! Otherwise you may develop manifestations of systemic effects of the drug.
In children under 6 years of age only nasal drops are used.
Vibrocil has no sedative effect (does not affect the speed of psychomotor reactions).
It can be used during lactation.
Phenylephrine (like other vasoconstrictors) is contraindicated in patients who are currently receiving MAO inhibitors or have received them in the previous 2 weeks.
Phenylephrine should not be prescribed concomitantly with tricyclic antidepressants, beta-adrenoblockers.
Contraindications
Hypersensitivity to the components of the drug.
Atrophic rhinitis (including with stinky discharge – ozenema). Taking MAO inhibitors (simultaneously or in the previous 14 days).
With caution, use in patients with arterial hypertension, arrhythmias, cardiovascular disease, and patients with generalized atherosclerosis, thyroid disease, closed-angle glaucoma, prostate adenoma, insulin-dependent diabetes.
As with any topical vasoconstrictors, caution should be exercised when prescribing Vibrocil to patients with significant reactions to sympathomimetics (e.g., with the development of insomnia and dizziness).
The drug is not recommended to be taken during pregnancy without a doctor’s recommendation.
Side effects
Mild and transient local reactions from the nasal mucosa (burning sensation or dryness).
Overdose
No serious side effects have been reported when Vibrocil was accidentally ingested by young children. In most cases there were no symptoms of overdose, however, sometimes such symptoms as fatigue, pain in the stomach, tachycardia, arterial hypertension, agitation, insomnia, pale skin (more often in children when accidentally taken orally) have been reported.
Treatment: use of activated charcoal, laxatives (gastric lavage is not required); in adults and children over 6 years – taking plenty of fluids. There is no specific antidote.
Similarities
Vibrocil, For cough and runny nose
Weight | 0.034 kg |
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Shelf life | 3 years. The product should not be used after the expiry date marked [EXP] on the package. |
Conditions of storage | Store at a temperature not exceeding 30 ° C. |
Manufacturer | GSC Consumer Healthcare S.A., Switzerland |
Medication form | dosed nasal spray |
Brand | GSC Consumer Healthcare S.A. |
Other forms…
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