🐾 Convenia lyophilizate, vial 10 ml

Convenia belongs to antibacterial drugs of III generation cephalosporins group.
Cefovecin – the active substance of Convenia has a broad spectrum of antibacterial activity against most gram-positive and gram-negative microorganisms, including Staphylococcus pseudintermedius and Pasteurella multocida, usually isolated in skin infections in dogs and cats; Prevotella oralis, Bacteroides spp. and Fusobacterium spp, isolated from abscesses in cats; Porphyromonas spp. and Prevotella spp. isolated in acute infections of the periodontium and gums in dogs; and Escherichia coli isolated in urinary tract infections in dogs and cats.
The mechanism of action of cefovecin lies in blocking enzymes of transpeptidases that bind peptidoglycan of cell wall, resulting in destruction of bacterial cell.
Cefovecin is rapidly absorbed from the injection site, reaching peak plasma concentrations in dogs after 6 hours, in cats – after 2 hours. Therapeutic concentrations of antibiotic after single drug administration in dogs and cats remain stable for 14 days.
Cefovecin binds with blood plasma proteins by more than 96% and is eliminated from the body mainly with urine unchanged. Half-life of the drug in dogs is 5.5 days, in cats – 6.9 days.
Convenience is classified as “low-hazardous substances” (4th class of danger according to GOST 12.1.007-76).

Indications

Ivermek is prescribed to animals with therapeutic and prophylactic purpose for arachnoentomoses and nematodoses:

– to cattle with strongylatosis, trichocephaliasis, strongyloidiasis, thelyasiasis, siphunculatosis, hypodermatosis, psoroptosis, sarcoptosis and chorioptosis;

– In sheep and goats in case of dictyocaulosis, protostrongylosis, muelleriosis, haemonchosis, ostertagiosis, nematodiroza, marshallagiosis, cooperiosis, esophagostomosis, bunostomosis, trichocephalesis, strongyloidosis, melophagosis, estrosis, psoroptosis and habertiosis;

– in deer in dictyocaulosis, ostertagiosis, nematodirosis, strongyloidiasis, trichocephaliasis, edemagenosis, cephenomyiasis and sarcoptosis;

– In camels against dictyocaulosis, ostertagiosis, nematodiroza, strongyloidiasis, trichocephalesis and sarcoptosis;

– In pigs against trichocephalesis, ascariasis, metastrongylosis, esophagostamiasis, strongyloidiasis, stefanurosis, hematopenosis and sarcoptosis.

Active ingredient

Cefovecin

Composition

Cefovecin – 852 mg and excipients: methyl parahydroxybenzoate, propyl parahydroxybenzoate, benzyl alcohol, sodium citrate dihydrate, hydrochloric acid and sodium chloride (for pH adjustment). Cefovecin diluent contains benzyl alcohol and water for injection.

How to take, the dosage

Convnix is used in dogs and cats in the form of solution for injection, which is prepared before use observing the rules of asepsis. In a bottle with antibiotic powder add the included solvent and shake thoroughly until its complete dissolution.

The prepared therapeutic solution containing 80 mg of cefovecin in 1 ml is administered singly subcutaneously at a dose of 1 ml per 10 kg of animal weight (equivalent to 8 mg of cefovecin per 1 kg of animal weight).

If necessary the drug shall be administered repeatedly in the same dose at 14 day intervals. The total course of treatment shall not exceed four injections.

Special Instructions

Empty packaging from the drug must not be used for domestic purposes, it must be disposed of with household waste. No peculiarities of action of the drug during its first use and withdrawal have been established. If it is necessary to reintroduce the drug it is necessary to avoid violation of the recommended interval between injections, because it may lead to a decrease in therapeutic efficacy. If another injection is missed, the drug should be administered as soon as possible in the same dose. The drug is not intended for use in productive animals.

Contraindications

Do not use the drug in dogs and cats with hypersensitivity to (beta-lactam antibiotics, pregnant females, puppies and kittens up to 8 weeks of age, as well as animals during mating.

Side effects

When using the drug in accordance with these instructions side effects and complications are usually not observed. In case of allergic reactions the drug shall be discontinued and antihistamines and symptomatic therapy shall be prescribed.