🐾 Sinulox tablets 250 mg, 10 pcs.

Pharmacotherapeutic group: antibacterial combination drug.

Amoxicillin is the active ingredient of Sinulox – a semisynthetic antibiotic of penicillin group.

The mechanism of antibacterial action of the antibiotic is inhibition of functional activity of bacterial enzymes of transpeptidases involved in the binding of the main component of the cell wall of microorganisms – peptidoglycan, which leads to the death of bacteria.

Clavulanic acid inactivates penicillinase of penicillin-resistant microorganisms and thus restores bacteria sensitivity to the bactericidal action of amoxicillin in concentrations that are easily achieved in animal tissues after administration of the drug. The combination of amoxicillin with clavulanic acid has a broad spectrum of antibacterial action against most Gram-positive and Gram-negative bacteria, including Staphylococcus spp. (including strains producing β-lactamase), Corynebacterium spp, Streptococcus spp., Clostridium spp., Peptostreptococcus spp., Escherichia coli (including β-lactamase producing strains), Salmonella spp. (including β-lactamase producing strains), Pasteurella spp, Klebsiella spp., Proteus spp., Fusobacterium necrophorum, Campylobacter spp.

Amoxicillin and clavulanic acid after oral administration are well absorbed from the gastrointestinal tract and penetrate into most body organs and tissues. Active ingredients of Sinulox are practically unmetabolized and excreted from the body mainly with urine and to a lesser extent with bile. According to the degree of impact on the body Sinulox refers to moderately hazardous compounds (4th class of hazard according to GOST 12.1.007).

Indications

Reptilife suspension is prescribed for turtles, lizards and snakes for prophylactic and therapeutic purposes against nematodosis and cestodosis.

Composition

Sinulox 250 mg containing amoxicillin 200 mg and clavulanic acid 50 mg.

As excipients the drug contains erythrosine (E 127), magnesium stearate, sodium glycolate (type A), anhydrous colloidal silicon, dry yeast and microcrystalline cellulose.

How to take, the dosage

The drug is given orally. Sinulox is given to cats and dogs by hand or mixed with food. Food intake does not affect the bioavailability of active substances of the drug. The drug is prescribed in a single dose of 12.5 mg (sum of the active substances) per 1 kg of animal weight twice a day. If the disease is difficult to treat (respiratory infections), Sinulox dosage should be increased to 25 mg/kg of animal weight twice daily. The duration of Sinulox treatment is 5-7 days. In the case of chronic or hard-to-treat diseases, especially deep pyoderma in dogs, the course of treatment may be 10-28 days.

Special Instructions

Empty packaging from the drug is stored in a special place and disposed with household waste. No peculiarities of action of Sinulox at the beginning of administration and its cancellation have been revealed. Skipping the next dose of the drug should be avoided, because it may lead to reduction of therapeutic efficacy. If one dose of the drug is missed, it should be administered as soon as possible. Then the treatment course should be resumed in the doses and regimen prescribed in the instruction. The drug is not intended for use in productive animals.

Contraindications

Do not use Sinulox in animals with hypersensitivity to β-lactam antibiotics.

Side effects

When prescribing the drug according to the instructions, adverse events and complications are usually not noted. In case of allergic reactions, use of the drug shall be discontinued and antihistamines or other symptomatic treatment shall be prescribed.