🐾 Amoxoil retard suspension vial, 100 ml

Amoxicillin is a semi-synthetic antibiotic of the penicillin group. It has a broad spectrum of bactericidal action against Gram-positive (staphylococci, streptococci, clostridia, listeria, corynebacteria, actinomycetes) and Gram-negative (Bordetella, Escherichia, Fusobacteria, Salmonella, Pasteurella, Haemophilius, Proteus, Moraxella) microorganisms as well as leptospira. Amoxicillin interferes with the synthesis of the bacterial cell membrane by inhibiting the enzymes of transpeptidase and carboxypeptidase and causing disruption of the osmotic balance, which leads to the death of the bacterium at the growth stage. When parenteral administration amoxicillin is well absorbed into the blood from the injection site and rapidly distributed in the body. Maximum concentration in plasma is reached 1 – 2 hours after administration of the drug and remains at a therapeutic level for 48 – 72 hours. Amoxicillin is practically not metabolized. It is excreted mainly with urine, to a lesser extent with milk and bile.

Indications

Prescribed for treatment of purulent wounds infected with mixed microflora (including staphylococci, Pseudomonas aeruginosa and E. coli).

Active ingredient

Amoxicillin

Composition

A long-acting antibacterial preparation containing 150 mg of amoxicillin trihydrate and a filler in 1 ml as an active ingredient.

How to take, the dosage

Amoxoyl retard is administered to animals intramuscularly or subcutaneously at a dose of 1 ml per 10 kg of animal weight. If necessary, the drug can be administered again in 48 hours. For animals with renal insufficiency it is recommended to check the exact dose of the drug. Before use the contents of the bottle shall be shaken thoroughly until a homogeneous suspension is obtained. Only dry sterile syringes and needles shall be used for administration of Amoxoil retard suspension. If administered dose of the drug exceeds 20 ml, it is recommended to inject it by several injections in different points. It is recommended to gently massage the injection site after administering Amoxoil Retard.

Special Instructions

Slaughter of animals for meat shall be allowed 14 days after cessation of drug administration. Meat of animals slaughtered before expiry of specified period can be used to feed fur animals or for production of meat and bone meal. Milk from animals injected with Amoxoyl retard suspension may be used for food purposes after 48 hours after cessation of treatment. Milk obtained from animals during the period of Amoxicillin administration and until 48 hours after the last drug administration shall be used to feed animals.

Contraindications

Hypersensitivity to amoxicillin and other penicillins. It should not be administered intravenously. Do not use in rabbits, hamsters, guinea pigs and gerbils. Amoxicillin should not be mixed with other drugs in the same syringe, and should not be used simultaneously with bacteriostatic chemotherapeutic agents. The drug should not be prescribed for infections caused by bacteria producing penicillinase.

Side effects

Allergic reactions to amoxicillin are possible in animals, which quickly disappear after discontinuation of the drug. Intoxication due to overdose is almost impossible. In case of allergic reactions it is advisable to administer corticosteroids and adrenaline to animals.