Xylenes, 0.05% drops 10 ml

Acute respiratory diseases with rhinitis (runny nose) phenomena; Acute allergic rhinitis; Pollinosis; Sinusitis; Eustachyitis; Middle otitis (as part of combined therapy to reduce nasopharyngeal mucosa edema); Preparing the patient for diagnostic manipulations in the nasal passages.

Active ingredient

Xylometazoline

How to take, the dosage

Hypersensitivity to xylometazoline or any of the excipients of the drug; Arterial hypertension; Tachycardia; Severe atherosclerosis; Glaucoma; Hyperthyroidism; Atrophic rhinitis; Inflammatory skin diseases or mucosa of the vestibule; Surgical interventions on the meninges (in anamnesis); Condition after transsphenoidal pituitaryectomy; Pregnancy; Use of monoamine oxidase inhibitors (MAOIs) (including 14 days after their withdrawal); Use of tricyclic or tetracyclic antidepressants; Childhood under 2 years old (for 0.05% solution); Childhood under 6 years old (for 0.1% solution).

With caution: Diabetes mellitus; Severe cardiovascular disease (incl. Coronary heart disease, angina pectoris); Prostatic hyperplasia; Pheochromocytoma; Porphyria; Breastfeeding period; Hypersensitivity to adrenergic drugs, accompanied by insomnia, dizziness, arrhythmia, tremor, increased blood pressure; Patients with prolonged QT interval syndrome.

Interaction

Xylometazoline is contraindicated in patients currently receiving MAO inhibitors or who have received them in the previous 2 weeks. Concomitant use of tri- or tetracyclic antidepressants and sympathomimetic drugs may increase the sympathomimetic effect of xylometazoline, so this combination should be avoided.

Special Instructions

The recommended doses should not be exceeded, especially in children and the elderly. Prolonged (more than 10 days) or excessive use of the drug may cause “ricochet” effect (rhinitis medica) and/or atrophy of the nasal mucosa. Patients with prolonged QT interval syndrome using xylometazoline may be at increased risk of developing serious ventricular arrhythmias. Benzalkonium chloride, which is part of the drug, may cause irritation of the nasal mucosa.

Influence on the ability to drive vehicles, machinery: The drug does not affect the ability to operate vehicles or equipment. When prolonged use in excess of the recommended doses we cannot exclude the possibility of its systemic effect. In such cases, caution should be exercised when driving vehicles or operating equipment.

Please read the full version of the instructions for medical use before using the drug. See the instructions for medical use for complete information.

Synopsis

Xylenum® drops 0,05% 10 ml is a vasoconstrictor based on xylometazoline for children from 2 to 6 years old for nasal breathing relief.

– Helps relieve nasal congestion during cold and allergic rhinitis, sinusitis
– It starts working within 2 minutes after application
– The effect can last up to 12 hours*

The drops are the most convenient and suitable for small children drug formulation. Xylen® drops 0,05% 10 ml is a convenient format to facilitate nasal breathing in children under 6 years.

* According to the instructions for medical use of Xylen® drops from 06.08.2021 (RU No: P002372/01) https://ksilen.expert/
There are CONTRAINDICATIONS. DO CONSULT A SPECIALIST
VER2202162-2 (v2.0) dated 07.10.2021
.

Contraindications

Hypersensitivity to xylometazoline or any of the excipients of the drug; Arterial hypertension; Tachycardia; Severe atherosclerosis; Glaucoma; Hyperthyroidism; Atrophic rhinitis; Inflammatory skin diseases or mucosa of the vestibule; Surgical interventions on the meninges (in anamnesis); Condition after transsphenoidal pituitaryectomy; Pregnancy; Use of monoamine oxidase inhibitors (MAOIs) (including 14 days after their withdrawal); Use of tricyclic or tetracyclic antidepressants; Childhood under 2 years old (for 0.05% solution); Childhood under 6 years old (for 0.1% solution).

With caution: Diabetes mellitus; Severe cardiovascular disease (incl. Coronary heart disease, angina pectoris); Prostatic hyperplasia; Pheochromocytoma; Porphyria; Breastfeeding period; Hypersensitivity to adrenergic drugs, accompanied by insomnia, dizziness, arrhythmia, tremor, increased blood pressure; Patients with prolonged QT interval syndrome.

Side effects

Immune system: hypersensitivity reaction (angioedema, rash, itching). Nervous system disorders: headache. Mental disorders: insomnia, depression (with prolonged use in high doses). Organs of vision: impairment of clarity of visual perception. Cardiac disorders: palpitations, tachycardia, arrhythmia. Vascular disorders: increase in blood pressure. Respiratory system, thorax and mediastinum organs: nasal mucosa irritation and/or dryness, burning, tingling, sneezing, hypersecretion of nasopharyngeal mucosa, after using the drug increased nasal mucosal edema (reactive hyperemia), nasal bleeding may be observed. Gastrointestinal disorders: nausea, vomiting. General disorders and reactions at the injection site: burning at the site of application.

Overdose

Xylomethasoline can cause severe dizziness, excessive local administration or accidental ingestion, increased sweating, rapid decrease in body temperature, headache, bradycardia, increased blood pressure, respiratory depression, coma and seizures. Following an increase in blood pressure, there may be a sudden drop in blood pressure. Appropriate supportive measures should be taken if there is any suspicion of overdose, in some cases immediate symptomatic treatment under medical supervision is indicated.

Similarities

Atrivin, Galazolin, Xylen, Snoop, Rinonorm, Xymelin Eco, Rinorus, Rinostop, Rinomaris, Xylometazolin, Tisin Classic, Xymelin Eco Menthol, Asterisk, Xyloct, Cold and Flu, Asterisk for Colds, Quatran xylo