Xylene, spray 0.05% 15 ml

Acute respiratory diseases with rhinitis (runny nose) phenomena; Acute allergic rhinitis; Pollinosis; Sinusitis; Eustachyitis; Middle otitis (as part of combined therapy to reduce nasopharyngeal mucosa edema); Preparing the patient for diagnostic manipulations in the nasal passages.

Active ingredient

Xylometazoline

How to take, the dosage

Intranasally. In children over 6 years of age and adults 1 injection in each nasal passage of 0.1% solution 2-3 times a day. In children aged 2 to 6 years 1 injection in each nasal passage of 0.05% solution 1-3 times a day. Do not use the drug more than 3 times a day. It is not recommended to use the drug for more than 5-7 days. The drug should be used in children under the supervision of adults. Consult a physician regarding the duration of use in children.

Interaction

Xylometazoline is contraindicated in patients currently receiving MAO inhibitors or who have received them in the previous 2 weeks. Concomitant use of tri- or tetracyclic antidepressants and sympathomimetic drugs may increase the sympathomimetic effect of xylometazoline, so this combination is contraindicated.

Special Instructions

The recommended doses should not be exceeded, especially in children and the elderly. Prolonged (more than 10 days) or excessive use of the drug may cause “ricochet” effect (rhinitis medica) and/or atrophy of the nasal mucosa. Benzalkonium chloride contained in the drug may cause irritation of the nasal mucosa.

Patients with prolonged QT interval syndrome who use xylometazoline may be at increased risk of developing serious ventricular arrhythmias.

Influence on the ability to drive vehicles, mechanisms

Xylometazoline does not affect the ability to drive vehicles, mechanisms.

Please read the full version of the instructions for medical use before using the drug. Full details are given in the instructions for medical use.

Synopsis

Xylen® Spray 0,05% 15 ml – product based on xylometazoline to relieve nasal congestion and make breathing easier in children from 2 to 6 years old.

– The effect can come in 2 minutes and lasts up to 12 hours*
– Xylometazoline (main active ingredient) has a more gentle effect on nasal mucosa and is well tolerated by people with sensitive mucosa**
– It relieves nasal congestion.

Xylen® Spray 0,05% 15 ml for children aged 2-6 years old to relieve nasal congestion and relieve breathing due to cold and allergic rhinitis.

* According to the instructions for medical use of the drug Xylen® spray from 11.06.2021 (RU No.: LP-000748) https://ksilen.expert/. ** Varvianskaya A.V., Lopatin A.S. Topical nasal decongestants: comparative characteristics and review of side effects. Russian rhinology. 2015;4:50-56

There are contraindications. MUST CONSULT WITH A SPECIALIST
VER2202162-2 (v2.0) of 07.10.2021
.

Contraindications

Hypersensitivity to xylometazoline or any of the excipients of the drug; Arterial hypertension; Tachycardia; Severe atherosclerosis; Glaucoma; Hyperthyroidism; Atrophic rhinitis; Inflammatory skin diseases or mucosa of the vestibule; Surgical interventions on the meninges (in anamnesis); Condition after transsphenoidal pituitaryectomy; Pregnancy; Use of monoamine oxidase inhibitors (MAOIs) (including 14 days after their withdrawal); Use of tricyclic or tetracyclic antidepressants; Childhood under 2 years old (for 0.05% solution); Childhood under 6 years old (for 0.1% solution).

With caution:

Diabetes mellitus; Severe cardiovascular disease (including. Coronary heart disease, angina pectoris); Prostatic hyperplasia; Pheochromocytoma; Porphyria; Breastfeeding period; Hypersensitivity to adrenergic drugs, accompanied by insomnia, dizziness, arrhythmia, tremor, increased blood pressure; Patients with prolonged QT interval syndrome.

Side effects

Immune system: very rare – hypersensitivity reactions (angioedema, rash, itching). Nervous system: often – headache. Mental disorders: rare – insomnia, depression (with prolonged use in high doses). Organs of vision: very rare – violation of clarity of visual perception. Heart: rare – a feeling of palpitations, very rare – tachycardia, arrhythmia. Vessels: rare – increase in blood pressure. Respiratory system, chest and mediastinum organs: often – irritation and / or dry nasal mucosa, burning, tingling, sneezing, hypersecretion of nasopharyngeal mucosa, rhinitis medication. Gastrointestinal disorders: frequently – nausea; rarely – vomiting. General disorders and reactions at the site of administration: often – burning at the site of application.

Overdose

Xylomethasoline can cause severe dizziness, excessive local administration or accidental ingestion, increased sweating, rapid decrease in body temperature, headache, bradycardia, increased blood pressure, respiratory depression, coma and seizures. Following an increase in blood pressure, there may be a sudden drop in blood pressure. Appropriate supportive measures should be taken if there is any suspicion of overdose, and in some cases immediate symptomatic treatment under medical supervision is indicated. These measures should include observation of the patient for several hours. In case of severe poisoning with cardiac arrest, resuscitation measures should last for at least 1 hour.

Pregnancy use

The drug should not be used during pregnancy. During breastfeeding the drug is used only after careful assessment of the risk-benefit ratio for the mother and the baby, under medical supervision. It is not allowed to exceed the recommended dosage.

Similarities

Atrivin, Galazolin, Xylen, Snoop, Rinonorm, Xymelin Eco, Rinorus, Rinostop, Rinomaris, Xylometazolin, Tisin Classic, Xymelin Eco Menthol, Asterisk, Xyloct, Cold and Flu, Asterisk for Colds, Quatran xylo