Polyoxidonium, tablets 12 mg 10 pcs

Pharmacotherapeutic group: immunomodulatory agent.

ATX code:[L0Z] Pharmacological properties

Pharmacodynamics

Azoximer bromide has a complex action: immunomodulatory, detoxifying, antioxidant, moderate anti-inflammatory.

The basis of the mechanism of immunomodulatory action of Azoximer bromide is a direct effect on phagocytic cells and natural killers, as well as stimulation of antibody formation and synthesis of interferon-alpha and interferon-gamma.

Indications

In adults and children over 3 years of age for the treatment and prevention of infectious and inflammatory diseases (viral, bacterial and fungal etiology) that are not amenable to standard therapy, both in the acute and remission stages.

In complex therapy:

acute and chronic recurrent infectious and inflammatory diseases of the oropharynx, paranasal sinuses, upper respiratory tract, inner and middle ear;
allergic diseases complicated by recurrent bacterial, fungal and viral infections (including hay fever, bronchial asthma);
for the rehabilitation of frequently and long-term (more than 4-5 times a year) ill persons.

As monotherapy:

for the prevention of recurrent herpetic infections;
for seasonal prevention of exacerbations of chronic foci of infections of the oropharynx, paranasal sinuses, upper respiratory tract, inner and middle ear;
in immunocompromised individuals for the prevention of influenza and other acute respiratory infections in the pre-epidemic period;
for the correction of secondary immunodeficiencies resulting from aging or exposure to adverse factors.

Pharmacological effect

Pharmacotherapeutic group: immunomodulatory agent.

ATX code:[L0З]
Pharmacological properties

Pharmacodynamics

Azoximer bromide has a complex effect: immunomodulatory, detoxifying, antioxidant, moderate anti-inflammatory.

The basis of the mechanism of immunomodulatory action of Azoximer bromide is a direct effect on phagocytic cells and natural killer cells, as well as stimulation of antibody formation and the synthesis of interferon-alpha and interferon-gamma.

Special instructions

If an allergic reaction develops, you should stop using Polyoxidonium® and consult a doctor.

If it is necessary to stop taking the drug Polyoxidonium®, withdrawal can be done immediately, without gradually reducing the dose.

If you miss the next dose of the drug, its subsequent use should be carried out as usual, as indicated in these instructions or recommended by your doctor. The patient should not administer a double dose to compensate for missed doses.

Do not use the drug if there are visual signs of its unsuitability (defective packaging, discoloration of the tablet).

Impact on the ability to drive vehicles and other machinery

The use of the drug Polyoxidonium® does not affect the ability to perform potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions (including driving vehicles, working with moving mechanisms).

Active ingredient

Azoximer bromide

Composition

1 tab. contains:

Active ingredient: Azoximer bromide – 12 mg;

Excipients: mannitol – 3.6 mg, povidone K 17 – 2.4 mg, lactose monohydrate – 185.0 mg, potato starch – 45.0 mg, stearic acid – 2.0 mg.

Pregnancy

Polyoxidonium is contraindicated during pregnancy, breastfeeding and children under 6 months (there is no clinical experience with its use).

Contraindications

Increased individual sensitivity;
pregnancy, breastfeeding period;
children under 3 years of age;
acute renal failure;
rare hereditary lactose intolerance, lactase deficiency, glucose-galactose malabsorption syndrome.

With caution

If you have the diseases listed in this section, consult your doctor before starting to take the drug: chronic renal failure (used no more than 2 times a week).

Side Effects

No side effects have been reported.

If you notice any side effects not listed in the instructions, tell your doctor.

Interaction

Azoximer bromide does not inhibit the isoenzymes CYP1A2, CYP2C9, CYP2C19, CYP2D6, cytochrome P-450, therefore the drug is compatible with antibiotics, antiviral, antifungal and antihistamines, glucocorticosteroids and cytostatics.

If you are taking the above or other medications (including over-the-counter medications), consult your doctor before taking Polyoxidonium.

Overdose

No cases of overdose have been reported.

Storage conditions

At temperatures from 2 to 25 °C. Keep out of the reach of children.

Shelf life

2 years. The drug should not be used after the expiration date indicated on the package.

Manufacturer

NPO Petrovax Pharm, Russia