Staphylococcus bacteriophage, 100 ml

Staphylococcus bacteriophage is an immunobiological drug, phage.

Staphylococcal bacteriophage has the ability to specifically lyse staphylococcal bacteria isolated in purulent infections, including Staphylococcus aureus.

Indications

Pharyngitis, Gastritis, Osteomyelitis, Dysbacteriosis, Arthritis, Intestinal infections, Enteritis, Burns, Tracheitis, Otitis, Lung inflammation (pneumonia), Purulent wounds, Arthritis, Bursitis, Cholecystitis, Angina, Urethritis, Furunculosis<> Staphylococcus bacteriophage is used for the treatment and prevention of purulent infections of the skin, mucous membranes, visceral organs caused by Staphylococcus bacteria.p> Staphylococcus bacteriophage is used for treatment and prevention of purulent skin, mucosal, visceral infections caused by staphylococcal bacteria, as well as in dysbacteriosis:

• diseases of the ear, throat, nose, respiratory tract and lungs (sinusitis, otitis media, angina, pharyngitis, laryngitis, tracheitis, bronchitis, pneumonia, pleurisy);
• Surgical infections (purulent wounds, infected burns, abscess, phlegmon, furuncle, carbuncle, hydradenitis, panaritis, infiltrated and abscessed staphylococcal sycosis, paraproctitis, mastitis, bursitis, tendovaginitis, osteomyelitis);
• Urogenital pathology (urethritis, cystitis, pyelonephritis, colpitis, endometritis, salpingo-oophoritis);
• enteric pathology (gastroenterocolitis, cholecystitis, intestinal dysbacteriosis);
• generalized septic diseases;
• pyoinflammatory diseases of newborns (omphalitis, gastroenterocolitis, sepsis);
• other diseases of staphylococcal etiology;
• prevention of purulent processes in freshly infected wounds (abdominal and thoracic surgery, street and occupational trauma, etc.).For the prevention of nosocomial infections for epidemic indications.

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Active ingredient

Staphylococcus aureus bacteriophage

Composition

The drug is a phagolysate filtrate active against staphylococcal bacteria of the most common phagotypes, including Staphylococcus aureus.

How to take, the dosage

The drug is used for oral administration (by mouth) rectal administration of applications of irrigations in the cavities of the wounds of the vagina of the uterus of the sinuses and drained cavities. The vial with bacteriophage must be shaken and viewed before use. The drug should be clear and without sediment.

The treatment of purulent-inflammatory diseases with localized lesions must be carried out simultaneously both locally and by oral administration of the drug 2-3 times a day on an empty stomach 1 hour before the meal from the first day of the disease within 7-20 days (according to clinical indications).

In case chemical antiseptics were used to treat wounds prior to the use of bacteriophage the wound must be thoroughly rinsed with sterile sodium chloride 09% solution.

Depending on the nature of the focus of infection bacteriophage is used:

1. In the form of irrigation of lotions and tamponage in the volume of up to 200 ml depending on the size of the affected area. In an abscess after removal of purulent contents by puncture, the drug is administered in an amount less than the volume of the removed pus. In case of osteomyelitis after appropriate surgical treatment 10-20 ml of bacteriophage is injected into the wound.
2. Injection into cavities (pleural articular and other limited cavities) up to 100 ml after which capillary drainage is left through which bacteriophage is administered for several days. If bladder cavity or renal pelvis are drained, bacteriophage shall be instilled through cystostoma or nephrostoma 1-2 times daily. 20-50 ml into the bladder and 5-7 ml into renal pelvis.In purulent inflammatory diseases of the ear, nose and throat the drug is administered in a dose of 2-10 ml 1-3 times a day. Bacteriophage is used for gargling, irrigation and eye-drop insertion of soaked turundas (leaving them for 1 hour).
3. In enteric infections with intestinal dysbacteriosis the drug is taken orally 3 times a day for 1 hour before the meal. Combination of twice-daily oral intake with single rectal administration of a single dose of bacteriophage in the form of enema after bowel emptying is possible.

Bacteriophage use in children (up to 6 months).

In case of sepsis enterocolitis of newborns including premature infants bacteriophage is used in the form of high enemas (through a gas tube or catheter) 2-3 times a day in a dose of 5-10 ml. In the absence of vomiting and regurgitation, it is possible to use the drug by mouth. In this case it is mixed with breast milk. A combination of rectal (in the form of high enemas) and oral (by mouth) administration of the drug is possible. The course of treatment is 5-15 days.

In case of recurrent course of the disease it is possible to carry out repeated courses of treatment. In order to prevent sepsis and enterocolitis in case of intrauterine infection or in case of risk of nosocomial infections in newborn children the bacteriophage is used as enema twice a day during 5-7 days.

In treatment of omphalitis pyoderma infected wounds the drug is used in the form of applications twice daily (a gauze cloth is wetted with the bacteriophage and applied to the umbilical wound or the affected area of the skin).

Interaction

The use of staphylococcal bacteriophage does not exclude the use of other medications.

Combination treatment with Staphylococcus aureus in combination with antibiotics is possible.

Special Instructions

Staphylococcus bacteriophage liquid is not suitable for use with turbidity and flakes.

Contraindications

Individual intolerance.

Side effects

No reactions to administration of staphylococcal bacteriophage have been established.

In intradermal injection there may be rapid reversible redness and inflammation.