Bacteriophage coliprophyte, 100 ml

How to take, the dosage

The drug is used for oral administration (by mouth), rectal administration, applications, irrigations, insertion into the cavities of wounds, vagina, uterus, nose, sinuses and drained cavities.

Recommended dosages of the drug:

• Patient age 0-6 months – 5 doses per 1 administration when administered orally (ml) – 5-10 doses per 1 administration when administered in an enema (ml).
• Patient age 6-12 months – 10 doses per dose when given orally (ml) – 10-20 doses per dose when given in enema (ml).
• Patient age from 1 year to 3 years – 15 doses per dose when given orally (ml) – 20-30 doses per dose when given in enema (ml).
• Patient age 3 to 8 years – 15-20 doses per dose when given orally (ml) – 30-40 doses per dose when given in enema (ml).
• Patient age 8 years and older – 20-30 doses per dose when given orally (ml) – 40-50 doses per dose when given in enema (ml).

The treatment of purulent inflammatory diseases with localized lesions should be carried out simultaneously both topically and by oral administration of the drug for 7-20 days (according to clinical indications).

In case chemical antiseptics were used for treatment of wounds prior to the use of bacteriophage, the wound must be thoroughly rinsed with sterile 0.9% sodium chloride solution.

Depending on the focus of infection bacteriophage is used:

1. In the form of irrigation, lotions and tamponage in the volume of up to 200 ml depending on the size of the affected area. In case of abscess after removal of purulent contents by puncture, the drug shall be administered in an amount less than the volume of the removed pus. In case of osteomyelitis after appropriate surgical treatment 10-20 ml of bacteriophage is injected into the wound.
2. Injection into cavities (pleural, articular and other limited cavities) up to 100 ml, after that capillary drainage is left, through which bacteriophage is administered for several days. If bladder cavity or renal pelvis are drained, bacteriophage shall be instilled through cystostoma or nephrostoma 1-2 times daily. 20-50 ml into the bladder and 5-7 ml into renal pelvis.In purulent inflammatory diseases of ear, throat and nose the drug is administered in a dose of 2-10 ml 1-3 times a day. Bacteriophage is used for gargling, irrigation, eye-drop, introduction of soaked turundas (leaving them for 1 hour).
3. In case of enteric infections, dysbacteriosis of bowel the preparation is taken orally 3 times a day 1 hour before the meal. Combination of twice-daily oral intake with single rectal administration of a single dose of bacteriophage in the form of an enema after the bowel emptying is possible.

   In case of sepsis, enterocolitis of newborns, including premature infants, bacteriophage is used as high enemas (through a gas tube or catheter) 2-3 times a day in a dose of 5-10 ml. In the absence of vomiting and regurgitation, it is possible to use the drug by mouth. In this case it is mixed with breast milk. A combination of rectal (in the form of high enemas) and oral (by mouth) administration of the drug is possible. The course of treatment is 5-15 days. In a recurrent course of the disease it is possible to carry out repeated courses of treatment. In order to prevent sepsis and enterocolitis in case of intrauterine infection or danger of nosocomial infections in newborn children the bacteriophage is used as enema twice a day for 5-7 days.

   In treatment of omphalitis, pyoderma, infected wounds the drug is used in the form of applications twice daily (a gauze cloth is wetted with bacteriophage and put on the umbilical wound or the affected area of skin).

Interaction

The use of the drug is possible in combination with other medicines, including antibiotics.

Special Instructions

Do not use the product if it is cloudy!

Because of the nutrient medium in the product, in which bacteria from the environment can develop and cause clouding of the product, the following rules should be observed when opening the vial:

• Wash hands thoroughly.
• Wash the cap with an alcohol-containing solution.
• Do not open the cap.
• Do not place the inner surface of the cap on a table or other objects.
• Do not leave the bottle open.
• Store opened bottle in refrigerator only.

When using small doses (2-8 drops), the drug must be taken with a sterile syringe of 0.5-1 ml.

The drug from an opened vial may be used for the entire shelf life if the storage conditions, the above rules and absence of turbidity are observed.

Impact on driving and operating ability

No.

Contraindications

Hypersensitivity to the ingredients of the drug.

Side effects

Not set.

Pregnancy use

The use of this medicinal product during pregnancy and lactation is possible in the presence of infections caused by phage-sensitive strains of bacteria (on the doctor’s recommendation).