Picamilon, 4 mg/ml 100 ml

Pharmacotherapeutic group

Notropic agent

ATX code: N06BX

Pharmacodynamics:

Notropic agent dilates cerebral blood vessels. Has a tranquilizing and mild psychostimulant action antiaggregant and antioxidant effect. Improves functional status of the brain due to normalization of tissue metabolism and its effect on cerebral circulation (increases the volumetric and linear velocity of the cerebral blood flow has a vasodilating antiaggregant antioxidant effect improves microcirculation). With a course of treatment increases physical and mental performance reduces headache improves memory normalizes sleep; helps reduce or disappearance of anxiety tension fear of emotional intemperance. Helps restore central motor and speech disorders of vascular or traumatic genesis. Improves blood circulation in the vessels of the retina and optic nerve.

Pharmacokinetics: Absorption is fast and complete in all routes of administration. It penetrates through the blood-brain barrier and is retained in the body tissues for a long time. Bioavailability is 50-88%. It is eliminated mainly by kidneys unchanged. The elimination half-life is 0.51 hours.

Indications

For adults:

– chronic cerebrovascular insufficiency (dyscirculatory encephalopathy, consequences of cerebrovascular accident) condition after traumatic brain injury, autonomic dystonia syndrome as part of complex therapy of depressive disorders of various origins in old age.

– as part of complex treatment for chronic alcoholism (reduction of asthenic asthenoneurotic postpsychotic pre-relapse conditions in alcoholic encephalopathy).

– as part of complex therapy for primary open-angle glaucoma with compensated intraocular pressure (to stabilize visual function).

– as part of complex therapy of vegetative dystonia syndrome accompanied by anxiety, fear, increased irritability, asthenia, emotional lability.

– to improve the tolerance of physical and mental stress and increase stress resistance (for persons under intense and extreme conditions of activity; to restore the physical performance of athletes to increase resistance to physical and mental stress).

For children over 3 years of age and adults in urological practice for urinary disorders to improve the adaptive function of the bladder (reducing detrusor hypoxia).

Pharmacological effect

Pharmacotherapeutic group

nootropic agent

ATX code: N06BX

Pharmacodynamics:

The nootropic agent dilates the blood vessels of the brain. It has a tranquilizing and mild psychostimulating effect, an antiplatelet and antioxidant effect. Improves the functional state of the brain by normalizing tissue metabolism and influencing cerebral circulation (increases the volumetric and linear velocity of cerebral blood flow, has a vasodilating antiplatelet antioxidant effect, improves microcirculation). When taken as a course, it increases physical and mental performance, reduces headaches, improves memory, normalizes sleep; helps reduce or eliminate feelings of anxiety, tension, fear of emotional incontinence. Promotes the restoration of central motor and speech disorders of vascular or traumatic origin. Improves blood circulation in the vessels of the retina and optic nerve.

Pharmacokinetics:
Absorption is fast and complete for any route of administration. Penetrates the blood-brain barrier and remains in the tissues of the body for a long time. Bioavailability – 50-88%. It is excreted mainly by the kidneys unchanged. The half-life is 0.51 hours.

Special instructions

Impact on the ability to drive vehicles. Wed and fur.:
The drug may have a negative effect on the performance of potentially hazardous activities that require special attention and speed of reaction (driving a car, operating moving mechanisms, etc.).

Active ingredient

Nicotinoyl gamma-aminobutyric acid

Composition

Active substance

Sodium nicotinoyl gamma-aminobutyrate – 100 mg

Excipients:

0.1 M hydrochloric acid solution – to pH from 6.7 to 8.0

Water for injection – up to 1 ml

Contraindications

Hypersensitivity chronic renal failure pregnancy lactation period children under 3 years of age (in children over 3 years of age it is used for urinary disorders).

Side Effects

Decreased blood pressure dizziness headache mild nausea irritability agitation anxiety allergic reactions (skin rash itching).

Interaction

Shortens the effect of barbiturates and enhances the effect of narcotic analgesics.

Overdose

Increased severity of dose-dependent symptoms of side effects. Treatment is symptomatic.

Storage conditions

In a place protected from light at a temperature not exceeding 25 C.

Keep out of the reach of children.

Shelf life

3 years.

Do not use after the expiration date indicated on the package.

Manufacturer

Pharmstandard-Leksredstva, Russia