Metrogil Dent, dental gel 20 g

The effectiveness of the drug is due to the presence in its composition of two antibacterial components:

a) metronidazole has antibacterial action against anaerobic bacteria causing periodontal disease: Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium fusiformis, Wolinella recta, Eikenella corrodens, Borrelia vincenti, Bacteroides melaninogenicus, Selenomonas spp.

b) chlorhexidine is an antiseptic and antimicrobial agent, effective against Gram-positive and Gram-negative aerobic and anaerobic bacteria (Treponema spp., Neisseria gonorrhoeae, Trichomonas spp., Chlamydia spp., Ureaplasma spp., Bacteroides fragilis). Some strains of Pseudomonas spp., Proteus spp. are slightly sensitive to the drug, as well as acid resistant forms of bacteria and bacterial spores are resistant. It does not impair the functional activity of lactobacilli.

When applied topically, Metrogil Denta gel is practically not absorbed.

Indications

Infectious and inflammatory diseases of periodontal and oral mucosa:

– acute and chronic gingivitis;
– acute ulcerative-necrotizing gingivitis of Vincent;
– acute and chronic periodontitis;
– juvenile periodontitis;
– periodontal disease complicated by gingivitis;
– aphthous stomatitis;
– cheilitis;
– inflammation of the oral mucosa when wearing dentures;
– post-extraction alveolitis (inflammation of the socket after tooth extraction);
– periodontitis, periodontal abscess (as part of combination therapy).

Pharmacological effect

The effectiveness of the drug is due to the presence of two antibacterial components in its composition:

a) metronidazole has an antibacterial effect against anaerobic bacteria that cause periodontal diseases: Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium fusiformis, Wolinella recta, Eikenella corrodens, Borrelia vincenti, Bacteroides melaninogenicus, Selenomonas spp.

b) chlorhexidine is an antiseptic and antimicrobial agent, effective against gram-positive and gram-negative aerobic and anaerobic bacteria (Treponema spp., Neisseria gonorrhoeae, Trichomonas spp., Chlamydia spp., Ureaplasma spp., Bacteroides fragilis). Some strains of Pseudomonas spp., Proteus spp. are weakly sensitive to the drug, and acid-resistant forms of bacteria and bacterial spores are also resistant. Does not interfere with the functional activity of lactobacilli.

When applied topically, Metrogyl Denta gel is practically not absorbed.

Special instructions

The use of Metrogyl Denta® does not replace hygienic brushing of teeth, therefore, during the course of treatment with the drug, teeth brushing should be continued.

The drug should be stored out of the reach of children. If the drug is accidentally or intentionally swallowed by a child, seek immediate medical attention.

If the medicine has become unusable or has expired, do not throw it into wastewater or onto the street! Place the medication in a bag and place it in the trash. These measures will help protect the environment!<

Active ingredient

Metronidazole

Composition

1 g of gel contains:

Active ingredients:

Metronidazole benzoate – 16.0 mg (equivalent to metronidazole – 10.0 mg)

Chlorhexidine digluconate 20% solution – 2.5 mg (equivalent to chlorhexidine digluconate – 0.5 mg)

Excipients:

propylene glycol 50.0 mg,

carbomer-980 15.0 mg,

disodium edetate 0.5 mg,

saccharin 1.0 mg,

levomenthol 5.0 mg,

sodium hydroxide 4.0 mg,

water up to 1 g.

Pregnancy

Due to the lack of clinical data, the safety of the drug during pregnancy and breastfeeding has not been established. The use of the drug during pregnancy is not recommended.

During the period of breastfeeding, if it is necessary to prescribe the drug, the issue of stopping breastfeeding should be decided.

Contraindications

hypersensitivity to metronidazole, chlorhexidine, nitroimidazole derivatives or other components of the drug;
diseases of the blood system, including a history;
diseases of the peripheral and central nervous system;
children under 18 years of age.

Side Effects

When using the drug Metrogyl Denta® topically, dental gel, allergic reactions (skin rash, itching, urticaria, anaphylactic reactions, including anaphylactic shock), as well as headache, may occur.

Interaction

When applied topically in recommended doses, no systemic interaction of Metrogyl Denta® gel with other drugs was detected.

Overdose

Accidental or intentional ingestion of a large amount of gel may cause increased side effects, mainly caused by metronidazole (chlorhexidine is practically not absorbed from the gastrointestinal tract). The following may be observed: nausea, vomiting, dizziness, and in more severe cases – paresthesia and convulsions.

Treatment: gastric lavage, symptomatic therapy if necessary.

Short product description

Thanks to the powerful combination of chlorhexidine and metronidazole, Metrogyl Denta® has an antiseptic and antibacterial effect on a wide range of organisms that cause gum inflammation.

Storage conditions

At a temperature not exceeding 25 °C
Keep out of the reach of children.

Shelf life

3 years. Do not use after expiration date.

Manufacturer

Unique Pharmaceutical Laboratories, India