Pharmacotherapeutic group: Hemorrhoids herbal remedy
ATX code C05AX
Pharmacological ACTIVITY
A combination drug; has antispasmodic (marsupial extract) and anti-inflammatory (ichthyol) effects.
Indications
Hemorrhoids, anal fissuresHemorrhoids, anal fissures.
Composition
Active substances: eyebright extract – 15 mg (with the amount of alkaloids in terms of hyoscyamine 1.5% – 0.225 mg), ichthamol (ichthiol) – 200 mg;
Auxiliary substances: purified water, emulsifier T-2, solid fat (Vitepsol brand H 15, W 35, suppository brand NA 15, NAS 50).
How to take, the dosage
Rectally, after a purging enema or self-emptying of the bowels. Use 1 suppository 1-3 times a day, but not more than 10 suppositories a day. Usually the course of treatment is 7-10 days.
Interaction
Simultaneous use with tricyclic antidepressants may increase the m-cholinoblocking effects of the drug (dry mouth, accommodation disorders, tachycardia, constipation, etc.).
When used with drugs that increase heart rate (including procainamide) – pronounced tachycardia is possible.
Monoamine oxidase inhibitors (MAO) increase the risk of side effects and enhance the positive chrono- and batmotropic effect; when combined with cardiac glycosides – increase the positive batmotropic effect.
Simultaneous administration of ethanol (alcohol) with Krasavka (belladonna) preparations may increase inhibitory effect on the central nervous system (CNS).
Special Instructions
Possible penetration of krasavka alkaloids through the blood-brain barrier and possible interaction with drugs affecting CNS should be taken into account. In therapeutic doses, urticaria alkaloids have a moderate stimulating effect on the CNS, in high doses – excitatory effect, in toxic doses – agitation, hallucinations, followed by inhibition and coma. Simultaneous prescription of the drug and other drugs with anticholinergic activity should be avoided, because the probability of side effects increases. Belladonna extract promotes reduction of the speed of absorption of concomitantly administered drugs due to inhibition of motor function of the gastrointestinal tract.
Influence on the ability to drive vehicles and operate mechanisms
During the treatment, caution should be exercised when driving vehicles and engaging in other potentially dangerous activities that require high concentration, rapid psychomotor reactions and good vision.
Contraindications
Hypersensitivity to the drug components, closed-angle glaucoma, benign prostatic hyperplasia, obstructive diseases of the gastrointestinal tract, bowel atony, active ulcerative colitis, chronic heart failure in the decompensation stage, tachycardia, myasthenia, pregnancy, breast-feeding, age under 18 years.
With caution
Vegetative neuropathy, hyperthyroidism, coronary heart disease, chronic heart failure, mitral stenosis, kidney diseases, hernia of the esophageal orifice of the diaphragm, reflux esophagitis, increased body temperature (possibility of fever and heat stroke due to suppression of sweat glands activity).
Side effects
Dry mouth, thirst, constipation, tachycardia, mydriasis, accommodation paresis, dizziness, photophobia, urinary retention, allergic reactions.
Overdose
Symptoms: dry mucous membrane of the mouth and nose, thirst, constipation, tachycardia, mydriasis, accommodation paresis, dizziness, photophobia, decreased sweating, urinary retention; in more severe cases – psychomotor agitation, seizures, acute urinary retention.
In case of overdose the drug should be discontinued and consult a physician.
Treatment: symptomatic.
Pregnancy use
Administration of the drug during pregnancy and breast-feeding is contraindicated. If it is necessary to use the drug during lactation, breastfeeding should be discontinued.
Weight | 0.023 kg |
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Shelf life | 2 years. Do not use the drug after the expiration date. |
Conditions of storage | Store in the dark place at a temperature not exceeding 20 ° C. Keep out of reach of children. |
Manufacturer | Nizhpharm AO, Russia |
Medication form | rectal suppositories |
Brand | Nizhpharm AO |
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