Hepatrombin G,ointment 20 g
€12.17 €10.14
“Combination drug. Heparin is a direct-acting anticoagulant, when used externally it has antithrombotic, antiexsudative and moderate anti-inflammatory effect; promotes regeneration of connective tissue, prevents blood coagulation in hemorrhoidal nodes.
Prednisolone is a glucocorticoid and has anti-inflammatory, anti-exudative and anti-allergic effects; it reduces inflammation and associated sensations (itching, burning, pain) in the anorectal area.
Polidocanol has a local anesthetic effect and provides sclerosis of hemorrhoidal nodes.”
Indications
Anal fissures, Hemorrhoids
External and internal hemorrhoids.
Thrombophlebitis of the hemorrhoidal veins of the anus.
Fistulas, eczema and itching in the anus area.
Cracks of the anus.
Preparing for surgical intervention in the anorectal area.
As part of the complex therapy of thrombosed or operated hemorrhoids.
.
Composition
1 g of the drug contains:
acting ingredients:
Sodium heparin – 65 ME;
(1 ME of sodium heparin is anticoagulant activity, corresponding to the activity of 0.0077 mg of the International Standard Heparin II (WHO))
Prednisolone acetate, 2.233 mg;
Lauromacrogol 600, 30.00 mg.
Auxiliary substances:
Paraffin solid
Liquid paraffin
Lanolin
Silicon dioxide colloidal.
How to take, the dosage
Externally, the ointment is applied to the affected areas in a thin layer 2-4 times a day; once the painful sensations have disappeared, apply once a day for 7 days.
The ointment is injected using the attached screw cap, which is inserted in the rectal cavity and a small amount of ointment is squeezed gently on the tube.
Special Instructions
As with all other corticosteroids, care should be taken not to use the drug in large quantities or for long periods.
The drug does not affect the ability to drive motor vehicles and potentially dangerous machinery.
Synopsis
Yellowish-white translucent, gel ointment with a characteristic odor of lanolin.
Features
Heparin
After adsorption the binding to plasma proteins is 95%.
It is excreted from the tissues slowly with a half-period of excretion about 1 hour. 50% of the active substance remains on the skin after administration. Release rate depends on the dose.
After absorption it is metabolized in the liver (partially by hepatic heparinase enzyme) and in reticuloendothelial system.
20-50 % is excreted unchanged in the urine and partially as uroheparin with weak anticoagulant effect.
The degree of excretion depends on the dose (lower doses have a shorter half-life in plasma).
Prednisolone
Prednisolone is metabolized in the liver after absorption.
About 1% is excreted unchanged in the urine.
Biological T1/2 is 18-36 h, and T1/2 from plasma is 115-212 min.
Contraindications
- high sensitivity to the components of the drug;
- bacterial, viral, fungal skin lesions;
- tuberculosis;
- syphilis;
- tumors of the skin (anorectal area);
- predisposition to bleeding;
- reactions to vaccination;
- I trimester of pregnancy.
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Side effects
With prolonged use and/or when applied to large surfaces there may be systemic side effects: slowing down the regeneration of cracks, edema.
Weight | 0.035 kg |
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Shelf life | 3 years. Do not use after the expiration date printed on the package. |
Conditions of storage | Store at 15 to 25 ° C. Keep out of reach of children! |
Manufacturer | Chemopharm A.D., Serbia |
Medication form | ointment for rectal and external use |
Brand | Chemopharm A.D. |
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