Cefecon N for adults, rectal 10 pcs

Cefecon N has analgesic, antipyretic and anti-inflammatory effects.

Naproxen and salicylamide are NSAIDs, whose mechanism of action is associated with inhibition of GH synthesis and influence on the thermoregulation center in the hypothalamus.

Caffeine has psychostimulant, analeptic and antispasmodic effect on smooth muscles, stimulates striated transverse muscles, reduces platelet aggregation and releases histamine from mast cells.

Indications

Lumbago, Toothache, Sciatica, Neuralgia, Myositis, Flu, Osteoarthritis, Neuritis, Osteochondrosis, Headache, Painful menstruation (algodysmenorrhea), Pain, Migraine, Pain in joints (arthralgia), Back pain, Myalgia (muscle pain)

Cefekon N is indicated as a pain reliever for pain syndromes of different severity:

• sciatica;
• dental pain;
• lumbago;
• neuralgia;
• migraine, headache;
• degenerative-dystrophic diseases of the musculoskeletal system (ankylosing spondylitis, osteoarthritis, osteochondrosis);
• myalgia;
• primary algodysmenorrhea.

As an antipyretic, it is used for febrile syndrome during infectious, inflammatory or colds.

Active ingredient

Caffeine, Naproxen, Salicylamide

Composition

One suppository contains:

Active ingredients:

Caffeine – 50 mg,

Naproxen – 75 mg,

Salicylamide – 600 mg;

Excipients:

Solid fat (Vitepsol, grades H 15, W 35, Supposir, grades NA 15, NAS 50) – to obtain a suppository weight of 2.20 g.

How to take, the dosage

According to the instructions for Cefecon N suppositories, the suppositories may be used only after natural bowel emptying or purging enema.

One suppository per day is prescribed 1 to 3 times. It is inserted into the rectum, with the patient having to spend about 40 minutes in bed.

When used as an analgesic, it should not be used more than 5 days, as a fever reliever – no more than 3 days.

Interaction

Limits the hypotensive effect of beta-adrenoblockers, ACE inhibitors; increases the effect of anticoagulants, oral hypoglycemic agents – sulfonylurea derivatives.

.

Special Instructions

In case of itching or discomfort in the rectum, an enema with sunflower oil (1 tablespoon) should be administered and the drug should be temporarily discontinued.

Contraindications

Cefecon N is not used in these cases:

• bleeding;
• closed-angle glaucoma;
children under 16 years of age;
• the elderly;
• hepatic insufficiency;
• peptic ulcer;
• hypersensitivity;
• arterial hypertension;
• insomnia;
• renal failure;
• pregnancy;
• excitability;
• excessive excitability
• cardiovascular disease;
• breastfeeding;
• broncho obstruction;
• chronic heart failure.

.

Side effects

The following undesirable effects may occur as a result of taking the drug:

• melena, gastritis, constipation, stomatitis, vomiting, heartburn, hematemesis, esophagitis, ulcerative stomatitis, GI bleeding and ulcers or perforations, worsening Crohn’s disease or ulcerative colitis, flatulence, pancreatitis;
• leukopenia, neutropenia, hemolytic anemia, eosinophilia, agranulocytosis;
• anaphylactic reactions, bronchospasm, allergic reactions, angioedema;
• sleep disturbance, confusion, insomnia, depression, hallucinations;
• Cognitive disorders, seizures, anxiety, aseptic meningitis, dizziness, tremor, difficulty concentrating, increased reflexes, paresthesias, headache, anxiety, optic neuritis;
• corneal clouding, visual disturbance, optic disc edema, papillitis;
• hearing disorders;
• edema, heart failure, chest pressure, arrhythmia;
• vasculitis;
• hepatitis, increased liver enzymes, jaundice;
• polymorphic erythema, Stephen-Johnson syndrome, rash, lichen planus, photosensitivity, pustular reactions, alopecia, pruritus, lupus erythematosus, bruising, erythema nodosum, purpura, epidermal necrolysis, urticaria, increased sweating;
• muscular weakness, pain;
• nephrotic syndrome, frequent urination, glomerulonephritis, hematuria, renal failure, interstitial nephritis, elevated creatinine, renal necrosis (medullary);
• women’s infertility;
• fever, malaise, thirst, fatigue.

.

Overdose

The hypotensive effect of ACE inhibitors and beta-adrenoblockers is reduced when taking Cefecon N.

When taken with sulfonylurea derivatives (oral hypoglycemic agents, anticoagulants) increases their effect.

.