🐾 Stomorgyl tablets 2 mg, 20 pcs.

Active components of the drug – metronidazole and spiramycin show synergistic action against a wide range of pathogens, including protozoa. Spiramycin as a natural antibiotic of macrolide group is able to bind reversibly to ribosomes and inhibit protein synthesis in the microbial cell. It is active against Streptococcus spp. (including Streptococcus pneumoniae), Staphylococcus aureus, Meningococcus spp., Bordetella spp., Corynebacterium spp., Listeria monocytogenes, Clostridium spp, Mycoplasma mycoides, Chlamydia spp., Leptospira interrogans, Campylobacter spp., Haemophilus spp., Bacteroides nodosus, Fusobacterium spp. and protozoa: Toxoplasma gondii. Metronidazole disrupts respiratory processes in the cell, which causes death of pathogenic protozoa. In addition, in some species of anaerobes it has the ability to inhibit DNA synthesis and cause its destruction. It is active against Gram-positive anaerobes: Clostridium spp., Eubacterium spp., Helicobacter pylori and Gram-negative bacteroides and fusobacteria as well as protozoan trichomonas. When administered orally, the drug is well absorbed from the gastrointestinal tract (bioavailability is about 100%) and the maximum concentration of its components in blood is observed after 1.5 – 3 hours. According to the degree of effect on the body of warm-blooded animals the drug refers to low-hazardous substances and in the recommended doses does not have resorptive-toxic, mutagenic and sensitizing effect.

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