🐾 Onsior tablets 5 mg for dogs from 2.5 kg to 5 kg Elanco, 28 pcs.

Onsior tablets refers to non-steroidal anti-inflammatory drugs.
Robenacoxib, a part of the drug, is a non-steroidal anti-inflammatory drug of coxib group, is a selective specific COX-2 inhibitor and has anti-inflammatory and analgesic effect. COX is present in two forms: COX-1, the constitutive form of the enzyme, performs protective functions, including in the gastrointestinal tract and kidneys; COX-2, the inducible form of the enzyme, is responsible for the production of mediators, including PGEs, that cause pain, inflammation and fever. When administered orally, robustacoxib is rapidly absorbed in the intestine, entering the systemic bloodstream and most organs and tissues; more than 99% of robustacoxib is bound to plasma proteins. Its maximum plasma concentration is observed after 0.5 hours, bioavailability is 49% in cats and 62% in dogs when using tablets with food and 84% without food. Robenacoxib is metabolized in the liver, excreted mainly with bile (about 70% in cats and about 65% in dogs) and partially with urine; half-life of dogs is about 1.2 hours, of cats – 1.7 hours. Onsior™ tablets according to the degree of impact on the body refers to the moderately hazardous substances (3rd class of hazard according to GOST 12.1.007).

Special instructions

should not be used simultaneously with other non-steroidal anti-inflammatory drugs and within 24 hours after their withdrawal, diuretics, glucocorticosteroids, as well as angiotensin converting enzyme inhibitors and other drugs with a high degree of binding to serum proteins.

Side Effects

As a rule, no side effects or complications are observed when using the drug. Gastrointestinal disorders (vomiting, soft stool or diarrhea) are possible, but they resolve spontaneously and do not require the use of medications.

Contraindications

individual hypersensitivity of the animal to the components of the drug. Should not be used in animals with severe cardiac, renal or hepatic insufficiency. Do not use in pregnant or lactating animals or puppies under 3 months of age.

Active ingredient

Robenacoxib

Specifications

✅No. 1 in Russia among non-steroidal anti-inflammatory drugs for animals in terms of sales in the retail market. According to RNC Pharma® ABD “Audit of retail sales of Vet medicinal products in Russia” for 2021,”
✅ reaches maximum concentration in the blood within 30 minutes after administration,
✅concentrates at the site of inflammation and pain and reduces them,
✅minimal effect on vital organs (liver, kidneys, stomach).
✅applies only 1 time per day
✅ small tablet with beef flavor
✅suitable for all breeds of dogs and puppies from 3 months of age and weighing more than 2.5 kg,
✅Can be used for lifelong treatment of osteoarthritis
✅Elanco product, manufactured in France

Manufacturer

Elanco, France

Shelf life

4 years from the date of production. Do not use after expiration date.