Xylong, spray 0.1 mg+5 mg/dose 15 ml

Xylometazoline belongs to the group of local vasoconstrictors (decongestants) with alpha-adrenomimetic activity, causes narrowing of the blood vessels of the nasal cavity mucosa, restores the patency of nasal passages, facilitates nasal breathing. The action of the drug usually comes within a few minutes after application and lasts up to 10 hours.

Dexpanthenol is a vitamin of group B – a derivative of pantothenic acid.

Dexpanthenol is converted by the body into pantothenic acid, which is part of coenzyme A (Co-A) and is involved in the processes of acetylation, carbohydrate and fat metabolism, the synthesis of acetylcholine, corticosteroids, porphyrins; It stimulates skin and mucous membranes regeneration, normalizes cell metabolism, accelerates mitosis and increases collagen fibers strength.

It has regenerative, metabolic and mild anti-inflammatory effect.

Pharmacokinetics

Xylometazoline is almost not absorbed during topical application and its concentration in plasma is so low that it cannot be determined by modern analytical methods.

Dexpanthenol when applied topically is quickly absorbed by skin and converted into pantothenic acid, binds to plasma proteins (mainly beta-globulin and albumin). Its concentration in blood is 0.5-1 mg/l, in blood serum – 100 µg/l.

Pantothenic acid is not metabolized in the body (except for inclusion in Co-A) and excreted unchanged.

Indications

Active ingredient

Composition

How to take, the dosage

Interaction

Special Instructions

Nasal passages should be cleaned before use. Duration of use of the drug in children is determined after consultation with a physician.

Impact on the ability to drive vehicles and mechanisms

When using the drug in accordance with these instructions for use, the drug does not affect the ability to drive vehicles, mechanisms, but if any adverse events occur, one should refrain from performing the specified activities.

Contraindications

Hypersensitivity to the components of the drug, arterial hypertension, tachycardia, marked atherosclerosis, hypertheriosis, glaucoma, atrophic rhinitis, dry rhinitis, porphyria, prostatic hyperplasia, brain surgery (in anamnesis), concomitant use with monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants, pregnancy, breastfeeding, children under 6 years of age.

With caution

Diabetes mellitus, pheochromocytoma, diseases of the cardiovascular system (including coronary heart disease), hypersensitivity to the action of adrenergic drugs, accompanied by insomnia, dizziness, arrhythmias, tremors, increased blood pressure.

Side effects

Overdose

Pregnancy use

Similarities