Xylenum active, spray 0.1% 15 ml

Acute respiratory diseases with rhinitis (runny nose) phenomena; Acute allergic rhinitis; Pollinosis; Sinusitis; Eustachyitis; Middle otitis (as part of combined therapy to reduce nasopharyngeal mucosa edema); Preparing the patient for diagnostic manipulations in the nasal passages.

Active ingredient

Xylometazoline

How to take, the dosage

Intranasally. In children over 12 years of age and adults: 1 injection into each nasal passage of 0.1% solution 2-3 times a day. Do not use the drug more than 3 times a day. Do not use the drug for more than 5-7 days. The drug should be used in children under the supervision of adults. Consult a physician regarding the duration of use in children.

Interaction

Xylometazoline is contraindicated in patients currently receiving MAO inhibitors or who have received them in the previous 2 weeks. Concomitant use of tri- or tetracyclic antidepressants and sympathomimetic drugs may increase the sympathomimetic effect of xylometazoline, so this combination should be avoided.

Special Instructions

The recommended doses should not be exceeded, especially in children and the elderly. Prolonged (more than 10 days) or excessive use of the drug may cause “ricochet” effect (rhinitis medica) and/or atrophy of the nasal mucosa. Patients with prolonged QT interval syndrome using xylometazoline may be at increased risk of developing severe ventricular arrhythmias. Benzalkonium chloride contained in the drug may cause irritation of the nasal mucosa. The drug contains menthol and eucalyptol, which have a cooling effect on the nasal mucosa, giving a feeling of freshness.
Effect on the ability to drive vehicles, machinery
The drug does not affect the ability to operate vehicles or equipment. In case of long-term use in excess of the recommended doses, the possibility of its systemic action cannot be excluded. In such cases, caution should be exercised when driving vehicles or operating equipment.

Please read the full version of the instructions for medical use before using the drug. See the instructions for medical use for complete information.

Synopsis

Xylenum active® Spray 0,1% 15 g is a vasoconstrictor on the basis of xylometazoline with menthol and eucalyptus for adults and children over 12 years old.

– Helps to reduce swelling, eases breathing and eliminates nasal congestion
– The action of the drug starts after 2 minutes and can last up to 12 hours (for example, during the whole night)*
. – Well tolerated even if the nasal mucosa is sensitive, because it has a balanced pH*
– Menthol and eucalyptol cool the nasal mucosa, providing a feeling of freshness

Xylen active® Spray 0,1% 15 g – a double action Xylometazoline relieves nasal congestion for up to 12 hours, and menthol and eucalyptus give a feeling of freshness.

* According to the instructions for medical use of Xylenum active® Spray dated 08.06.2021 (PI №: LP-003492) https://ksilen.expert/
there are CONTRAINDICATIONS. DO CONSULT A SPECIALIST
VER2202162-2 (v2.0) dated 07.10.2021

Contraindications

Hypersensitivity to xylometazoline or any of the excipients of the drug; Arterial hypertension; Tachycardia; Severe atherosclerosis; Glaucoma; Hyperthyroidism; Atrophic rhinitis; Inflammatory skin diseases or mucosa of the vestibule; Cranial surgery (in anamnesis); Status after transsphenoidal hypophysectomy; Pregnancy; Use of monoamine oxidase inhibitors (MAOIs) (including 14 days after their withdrawal); Use of tricyclic or tetracyclic antidepressants; Children under 12 years old:
Diabetes mellitus; Severe cardiovascular disease (including coronary heart disease, angina pectoris); Prostate hyperplasia; Pheochromocytoma; Porphyria; Breastfeeding period; Hypersensitivity to adrenergic drugs, accompanied by insomnia, dizziness, arrhythmias, tremors, increased blood pressure; Patients with prolonged QT interval syndrome.

Side effects

Immune system: very rare – hypersensitivity reaction (angioneurotic edema, rash, itching). Nervous system: often – headache. Mental disorders: rare – insomnia, depression (with prolonged use in high doses). Organs of vision: very rare – violation of clarity of visual perception. Heart: rare – a feeling of palpitations, very rare – tachycardia, arrhythmia. Vessels: rare – increase in blood pressure. Respiratory system, thorax and mediastinum: frequently – irritation and / or dryness of the nasal mucosa, burning, tingling, sneezing, hypersecretion of nasopharyngeal mucosa, rarely – after using the drug increased nasal mucosal edema (reactive hyperemia) and nose bleeding may be observed. Gastrointestinal disorders: frequently – nausea; rarely – vomiting. General disorders and reactions at the injection site: often – burning at the application site.

Overdose

Xylomethasoline can cause severe dizziness, excessive local administration or accidental ingestion, increased sweating, rapid decrease in body temperature, headache, bradycardia, increased blood pressure, respiratory depression, coma and seizures. Following an increase in blood pressure, there may be a sudden drop in blood pressure. Appropriate supportive measures should be taken if there is any suspicion of overdose, and in some cases immediate symptomatic treatment under medical supervision is indicated. These measures should include observation of the patient for several hours. In case of severe poisoning with cardiac arrest, resuscitation measures should last for at least 1 hour.

Pregnancy use

During pregnancy the use of the drug is contraindicated. During breastfeeding the drug should be used only after careful assessment of the risk-benefit ratio for mother and child, it is not allowed to exceed the recommended dosage.

Similarities

Atrivin, Galazolin, Xylen, Snoop, Rinonorm, Xymelin Eco, Rinorus, Rinostop, Rinomaris, Xylometazolin, Tisin Classic, Xymelin Eco Menthol, Asterisk, Xyloct, Cold and Flu, Asterisk for Colds, Quatran xylo