Tsipromed, ear drops 3 mg/ml 10 ml

Ciprofloxacin is an antimicrobial drug from the group of fluoroquinolones with a broad spectrum of antibacterial action and bactericidal effect. The drug inhibits bacterial DNA-gyrase enzyme, which disrupts DNA replication and synthesis of bacterial cell proteins. Ciprofloxacin acts both on multiplying microorganisms and on those in a quiescent stage.

The spectrum of antibacterial action of ciprofloxacin includes Gram-negative microorganisms: Esherichia coli, Salmonella spp., Shigella spp., Proteus spp. (indole positive and indole negative), Morganella morganii, Citrobacter spp, Klebsiella spp., Enterobacter spp., Vibrio spp., Campylobacter spp., Hafnia spp., Providencia stuartii, Haemophilus influenzae, Pasteurella multocida, Pseudomonas spp., Gardnerella spp., Legionella pneumophila, Neisseria spp., Moraxella catarrhalis, Acinetobacter spp., Brucella spp., Chlamidia spp. Gram-positive microorganisms are also sensitive to ciprofloxacin: Staphylococcus spp., Streptococcus pyogenes, St. agalactiae, Corynebacterium diphtheriae, Listeria monocitogenes. The drug is slightly toxic.

Indications

Treatment of acute and chronic ear infections: otitis externa; acute and chronic otitis media.

Prevention of infectious otitis before and after surgery, in case of ear injuries, removal of a foreign body from the external auditory canal, accompanied by damage to ear tissue.

Pharmacological effect

Ciprofloxacin is an antimicrobial drug from the group of fluoroquinolones, has a wide spectrum of antibacterial action and has a bactericidal effect. The drug inhibits the enzyme DNA gyrase of bacteria, as a result of which DNA replication and the synthesis of bacterial cellular proteins are disrupted. Ciprofloxacin acts both on microorganisms that are reproducing and those in the dormant stage.

The spectrum of antibacterial action of ciprofloxacin includes gram-negative microorganisms: Esherichia coli, Salmonella spp., Shigella spp., Proteus spp. (indole-positive and indole-negative), Morganella morganii, Citrobacter spp., Klebsiella spp., Enterobacter spp., Vibrio spp., Campylobacter spp., Hafnia spp., Providencia stuartii, Haemophilus influenzae, Pasteurella multocida, Pseudomonas spp., Gardnerella spp., Legionella pneumophila, Neisseria spp., Moraxella catarrhalis, Acinetobacter spp., Brucella spp., Chlamidia spp. Gram-positive microorganisms are also sensitive to ciprofloxacin: Staphylococcus spp., Streptococcus pyogenes, St. agalactiae, Corynebacterium diphtheriae, Listeria monocitogenes. The drug is low toxic.

Active ingredient

Ciprofloxacin

Composition

1 ml ear drops contains:

active ingredient:

ciprofloxacin 3 mg,

excipients:

benzalkonium chloride,

lactic acid, propylene glycol.

Pregnancy

Contraindicated during pregnancy. Breastfeeding should be stopped during treatment.

Contraindications

Hypersensitivity to the components of the drug or to other quinolones,
pregnancy,
breastfeeding period,
children under 15 years of age.

Side Effects

In some cases, allergic reactions may develop.

Interaction

Ciprofloxacin solution is incompatible with drugs with a pH value of 3-4, which are physically and chemically unstable.

Overdose

There have been no cases of overdose when using ear drops.

In case of accidental ingestion, there are no specific symptoms, possibly nausea, vomiting, diarrhea, headache, dizziness, anxiety.

Treatment: it is necessary to ensure sufficient fluid intake, maintaining an acidic urine reaction to prevent crystalluria. If necessary, carry out symptomatic therapy.

Storage conditions

In a place protected from light, at a temperature not exceeding 25 °C (do not freeze)

Shelf life

2 years

Manufacturer

Sentiss Pharma Pvt.Ltd, India