Timogen, 0.05% cream 30 g

Timogen is an immunostimulant, a dipeptide.

It has immunomodulatory, anti-inflammatory, desensitizing, antioxidant, reparative effects. It interacts with T-lymphocytes, Langerhans cells (macrophages) and skin mast cells, normalizing their functional activity and intercellular interaction.

It helps to decrease antigen/IgE-mediated production of inflammatory mediators of the level of pro-inflammatory cytokines and biogenic amines (histamine and serotonin) in skin cells. Causes reduction of skin manifestations of allergic reactions in hypersensitivity to various allergens. Suppresses the inflammatory response in response to skin irritants in contact dermatitis. It reduces skin inflammation and itching in allergic dermatitis in the acute phase of the disease.

Inhibits free radical oxidation processes in pathologically changed skin cells, preventing their damage and death, stimulating the production of antioxidant protective factors of cells.

Stimulates the proliferation of keratinocytes, fibroblasts and endothelial cells, facilitating the regeneration of damaged skin. It accelerates wound healing and stimulates cellular and humoral (tissue) defense factors.

The systemic effects are negligible due to limited absorption through the skin

Indications

Active ingredient

Composition

1 g of cream for external use contains:

the active ingredient:

timogen (glutamyl-tryptophan monosodium salt) 500 mcg;

excipients:

Vaseline oil,

Vaseline,

Polyethylene glycol sorbitan monostearate, cetyl alcohol,

Diethylene glycol monoethyl ether,

methyl parahydroxybenzoate (nipagin),

xantham gum,

propylparahydroxybenzoate,

purified water

How to take, the dosage

The cream is applied thinly to the affected area 1-2 times a day (morning and evening). After applying the cream, the affected area should not be covered with a bandage.

The recommended daily dose is 2 g of cream (1000 mcg thymogen). A strip of cream which is 5 mm in diameter and 4 cm in length has a weight of 1 g.
Course duration: until the local manifestations of the disease have subsided, but not more than 20 days.

Interaction

It increases the effectiveness of other types of therapy (cytostatics, radiation therapy, etc.); it is not recommended to use simultaneously with high doses of glucocorticosteroid drugs.

Special Instructions

The results of clinical studies show that the drug Timogen in dosage form of cream meets the requirements for external therapy in the treatment of chronic dermatoses (atopic dermatitis, strophulus, microbial eczema and pyoderma) in children.

The drug reduces inflammation in the focus of infection reducing swelling and hyperemia of the skin, reduces itching, promotes fast restoration of skin integrity and eliminates its dryness thus improving the skin barrier function.

In addition, providing immunocorrective action, Timogen increases the protective function of the skin.

Contraindications

Individual intolerance to the drug, pregnancy, breastfeeding.

Side effects

Allergic reactions.

Pregnancy use

It is contraindicated in pregnancy and during lactation (breastfeeding).