Spazgan, tablets 100 pcs

Spazgan is a combined drug, it belongs to the group of aldehydic and antispasmodic agents.

The drug consists of: non-narcotic analgesic sodium metamizole (analgin), myotropic antispasmodic agent pythophenone hydrochloride and choline-blocking agent phenpiperinia bromide.

Methamisole is a derivative of pyrosolone. It has analgesic, antipyretic, and mild anti-inflammatory effects.

Pitophenone, like papaverine, has a direct myotropic effect on the smooth muscles of internal organs and causes them to relax.

Phenpiveryinia has an additional relaxing effect on the smooth muscles due to its cholin-blocking action.

The combination of the three components of the drug leads to a mutual strengthening of their pharmacological action.

Indications

Sciatica, Arthrosis and arthritis, Colic, Lumbago, Headache, Colds, Migraine, Radiculitis, Gastrointestinal spasms, Biliary dyskinesia

• Mild to moderately expressed pain syndrome in spasms of smooth muscles of internal organs – renal and hepatic colic, pain spastic in the bowel, algodysmenorrhea. It may be used for short-term symptomatic treatment of joint pain, neuralgia, ischialgia, myalgia.
• As an adjuvant, it may be used to reduce pain after surgical and diagnostic procedures.
• If necessary, the drug can be used to reduce the body temperature during colds and infectious and inflammatory diseases.

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Active ingredient

Sodium metamizole, Pitofenone, Phenpiperinia bromide

Composition

Each tablet contains:

active ingredients: metamizole sodium – 500 mg, pitophenone hydrochloride – 5.0 mg, phenpivery bromide – 0.1 mg;

excipients: lactose – 164.000 mg, magnesium stearate – 5.000 mg, colloidal silicon dioxide – 0.100 mg.

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How to take, the dosage

Orally: adults and adolescents over 15 years: 1-2 tablets 4 times a day, without chewing and drinking plenty of liquid.
Children 12-14 years old – a single dose of 1 tablet, the maximum daily dose – 6 tablets (1 tablet 4 times a day).5 tablets 4 times a day),
8-11 years – 0.5 tablets, the maximum daily dose – 4 tablets (1 tablet 4 times a day), 5-7 years – 0.5 tablets, the maximum daily dose – 2 tablets (0.5 tablets 4 times a day).

Interaction

Simultaneous use of Spazgan with other non-narcotic analgesics may lead to a mutual increase in toxic effects.

Tricyclic antidepressants, oral contraceptives, allopurinol impair metabolism of metamizole in the liver and increase its toxicity.

Barbiturates, phenylbutazone and other inducers of microsomal liver enzymes weaken the effects of metamizole. Concomitant use with cyclosporine reduces the blood levels of the latter. Sedatives and tranquilizers increase the analgesic effect of Spazgan.

If it is necessary to concomitantly use the above and other drugs, consult a physician.

Special Instructions

In patients suffering from bronchial asthma, taking this drug may provoke a seizure.

Contraindications

Hypersensitivity to pyrazolone derivatives (butadion, tribuzone), to other components of the drug. Inhibition of bone marrow hematopoiesis, stable and unstable angina pectoris, decompensated chronic heart failure, marked liver or renal dysfunction, glucose-6-phosphate dehydrogenase deficiency, tachyarrhythmia, closed-angle glaucoma, Prostate hyperplasia with a tendency to urinary retention, intestinal obstruction and megacolon, granulocytopenia, lactase deficiency, lactose intolerance, glucose-galactose malabsorption, pregnancy, lactation, children under 8 years old.

Side effects

• decrease in the number of white blood cells
• decrease in blood pressure
• disorders of kidney function
• allergic reactions.

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Overdose

Symptoms: vomiting, decreased blood pressure, drowsiness, confusion, nausea, vomiting, epigastric pain, liver and kidney dysfunction, seizures.

Treatment: Gastric lavage, administration of activated charcoal, symptomatic therapy.

Pregnancy use

Use of the drug in breastfeeding mothers requires discontinuation of breastfeeding.

Similarities

Spasmalin, Maxigan, Spasmalgon, Bral, Revalgin