Spazgan is a combination drug, belongs to the group of aldehydic and antispasmodic agents. The drug consists of: non-narcotic analgesic sodium metamizole (analginum), myotropic antispasmodic agent pitophenone hydrochloride and choline-blocking agent fenpiperinia bromide.
Methamisole is a derivative of pyrosolone. It has analgesic, antipyretic, and mild anti-inflammatory effects.
Pitophenone, like papaverine, has a direct myotropic effect on the smooth muscles of internal organs and causes them to relax.
Phenpiveryinia has an additional relaxing effect on the smooth muscles due to its cholin-blocking action.
The combination of the three components of the drug leads to a mutual strengthening of their pharmacological action.
Sciatica, Lumbago, Headache, Colic, Gastrointestinal spasms, Arthritis and arthritis, Radiculitis, Biliary dyskinesia, Colds, Toothache
- Pains of various origins
- spasms of the internal organs (renal colic, biliary colic
- Post-operative pains.li>Pain of various origins
- spasms of the internal organs (renal colic, biliary colic)
- postoperative pain. Brain vascular spasms.
Sodium metamizole, Pitofenone, Phenpiperinia bromide
Each tablet contains:
the active ingredients:
Sodium metamizole – 500 mg,
pitophenone hydrochloride – 5.0 mg,
phenpiperinia bromide – 0.1 mg;
Auxiliary substances: lactose – 164,000 mg, magnesium stearate – 5,000 mg, colloidal silicon dioxide – 0.100 mg.
How to take, the dosage
Adults are prescribed 1-2 tablets. Spazgan up to 4 times a day.
The maximum daily dose is not more than 8 tablets.
Simultaneous use of Spazgan with other non-narcotic analgesics may lead to a mutual increase in toxic effects.
Tricyclic antidepressants, oral contraceptives, allopurinol impair metabolism of metamizole in the liver and increase its toxicity.
Barbiturates, phenylbutazone and other inducers of microsomal liver enzymes weaken the effects of metamizole. Concomitant use with cyclosporine reduces the blood levels of the latter. Sedatives and tranquilizers increase the analgesic effect of Spazgan.
If it is necessary to concomitantly use the above and other drugs, consult a physician.
In patients suffering from bronchial asthma, taking this drug may provoke a seizure.
- ischemic heart disease
- adenoma of the prostate
- severe hepatic and renal insufficiency
- high sensitivity to the components of the drug.
- decrease in the number of white blood cells
- decrease in blood pressure
- disorders of kidney function
- allergic reactions.
Symptoms: vomiting, decreased blood pressure, drowsiness, confusion, nausea, vomiting, epigastric pain, liver and kidney dysfunction, seizures.
Treatment: gastric lavage, administration of activated charcoal, symptomatic therapy.
The use of the drug in breastfeeding mothers requires stopping breastfeeding.
Spasmalin, Maxigan, Spasmalgon, Bral, Revalgin
|Conditions of storage|
In a dry, light-protected place at a temperature not exceeding 25 °C
Wockhardt Ltd, India
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