SOVIGRIPP influenza vaccine, inactiv.subunit, 0.5 ml (1 dose) №10
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The vaccine represents surface glycoproteins (hemagglutinin and neuraminidase) isolated from purified virions of influenza virus types A and B, obtained from the virus-containing allantois fluid of chicken embryos from clinically healthy chickens, and diluted in phosphate-salt buffer solution, in complex with SOVIDON adjuvant.
Indications
For active annual preventive immunization against seasonal influenza vaccine without preservative is used in children from 6 months of age, adolescents and adults without age restrictions; vaccine with preservative – in adults from 18 years.
Vaccine is especially indicated:
1. Persons at high risk of illness and complications in case of influenza:
– persons over 60 years old; children of preschool age, schoolchildren;
– persons frequently ill with acute respiratory viral infections;
– People suffering from chronic somatic diseases, including diseases and malformations of cardiovascular, respiratory and central nervous system, chronic kidney diseases, metabolic diseases, diabetes, chronic anemia, allergic diseases (except for allergies to chicken proteins); congenital or acquired immunodeficiency, including those infected with human immunodeficiency virus.
2. persons who by the nature of learning and professional activities have a high risk of flu or infecting other persons:
– students;
– health care workers;
– workers in social, administrative, educational, service, public catering, transport and trade areas;
– military personnel, police.
How to take, the dosage
Vaccination is carried out annually in the fall and winter period. Vaccination is possible at the beginning of the epidemic rise of influenza.
Children over 3 years old, adolescents and adults without age restrictions vaccine is administered once intramuscularly in the upper third of the outer surface of the upper arm (in the deltoid muscle) in a vaccine dose of 0.5 ml.
Children aged 6 months to 3 years old the vaccine is given twice with 4 week interval into the anterior surface of the femur intramuscularly in a 0.25 ml (1/2 dose) vaccination dose according to the following injection schedule:
1. From an ampoule containing 0.5 ml (1 dose) of the drug, 0.25 ml of vaccine is taken with a sterile syringe having the appropriate graduation. The remainder of the vaccine in the ampoule should be disposed of immediately.
2. When using a syringe containing 0.5 ml of the drug, you must remove half of the contents by pushing on the syringe piston to the appropriate mark on the syringe. The patient is injected the remaining amount of vaccine (0.25 ml).
Opening of ampoules and the vaccination procedure is carried out in strict adherence to asepsis and antiseptics.
The drug in the opened ampoules/syringes should not be stored.
The drug in ampoules/syringes with altered physical properties (color, transparency), compromised integrity and labeling, expired shelf life, violations of storage and/or transportation regimes are NOT suitable for use.
Interaction
The vaccine can be administered against the background therapy of the underlying disease. Vaccination of persons receiving immunosuppressive therapy may be less effective.
Vaccine can be administered simultaneously with other inactivated vaccines (except for anti-rabies). In this case, contraindications to each of the used vaccines should be taken into account, the preparations should be injected into different areas of the body with different syringes.
Special Instructions
On the day of vaccination, vaccinated persons should be examined by a general practitioner/feldsher with obligatory thermometry.
Contraindications
Allergic reactions to chicken protein or other components of the vaccine.
2. Severe post-vaccination reactions (fever above 40ºC, swelling, hyperemia over 8 cm in diameter at the injection site) or post-vaccination complications (collapse, non-febrile seizures, anaphylaxis) to previous flu vaccine administration.
3. Pregnancy (when using vaccine with preservative);
4. Age under 18 years old (when using vaccine with preservative);
5. Age under 6 months.
Temporary contraindications:
1. Acute febrile states, acute infectious and noninfectious diseases, including the period of convalescence. Vaccination is usually carried out 2-4 weeks after recovery.
2. Chronic diseases in the acute stage, vaccination is carried out during the remission period. The possibility of vaccination of persons suffering from chronic diseases is determined by the attending physician, based on the condition of the patient.
3. In non-serious forms of acute respiratory viral and intestinal infections vaccination is carried out after normalization of temperature and/or disappearance of acute symptoms of the disease
Side effects
The vaccine is a highly purified drug and is well tolerated by the vaccinee.
The following reactions may develop:
Very common(>1/10):
– local reactions: pain on palpation, thickening, swelling and hyperemia of the skin at the injection site;
– systemic reactions: subfebrile temperature, malaise, headache.
These local and systemic reactions are transient and disappear within 1-2 days without the prescription of specific therapy.
Very rare (< 1/10 000):
– with high individual sensitivity allergic reactions may be observed: anaphylactic shock, angioedema, urticaria, rash (erythematous, papular), etc.
Weight | 0.038 kg |
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Manufacturer | Microgen NPO, Russia |
Medication form | solution for injection |
Brand | Microgen NPO |
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