Sialor Rhino, drops 0.01% 1 ml 5 pcs.

Oxymetazoline belongs to the group of alpha-adrenergic stimulants for local use. It has a vasoconstrictor effect. When administered intranasally it reduces swelling of the mucous membrane of the upper airways and nasal secretions.

Restores nasal breathing. Elimination of nasal mucous membrane edema helps restore aeration of paranasal sinuses, middle ear cavity which reduces the possibility of bacterial complications (maxillary sinusitis, sinusitis, otitis media).

In local intranasal application in therapeutic concentrations it does not irritate and does not cause nasal mucous membrane hyperemia. The drug starts to work quickly, within a few minutes. The duration of action of the drug is up to 12 hours.

Pharmacokinetics< br>

In local intranasal administration, oxymetazoline has no systemic action. The half-life of oxymetazoline when administered intranasally is 35 hours. 2.1% of oxymetazoline is excreted with urine and about 1.1% with feces.

Indications

• Treatment of acute respiratory diseases accompanied by runny nose
• Allergic rhinitis
• Vasomotor rhinitis
• Rhinitis.
• reestablishing nasal sinus inflammation, eustachitis, otitis media;
• and for treating swelling before diagnostic manipulations of the nasal passages.

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Active ingredient

Oxymetazoline

How to take, the dosage

Intranasally.

• Adults and children over 6 years of age: use 1 to 2 drops of the 0.05% solution in each nasal passage 2 to 3 times a day.

The drug is not recommended for more than 7 days. Frequent and prolonged use may cause nasal congestion or worsen it. If these symptoms occur, discontinue treatment and consult a physician.

Interaction

In concomitant use with monoamine oxidase inhibitors (including the period within 14 days after their withdrawal), tricyclic antidepressants or other drugs that contribute to increased blood pressure, increased blood pressure may be observed. The drug slows absorption of local anesthetic drugs, prolonging their effect.

The co-administration of other vasoconstrictors increases the risk of side effects.

If you are using the above or other medications (including over-the-counter medications), please consult your physician before using Cialor®rino.

Special Instructions

Use in the recommended dose without consulting a physician for no more than 7 days. If symptoms worsen or do not improve within 3 days, consult a physician. Avoid contact with eyes.

The drug should be used individually to avoid spreading infection. After opening, use within 14 days.

Long-term use and overdose of oxymetazoline may weaken the therapeutic effect and increase the risk of reactive hyperemia (medicated rhinitis) and atrophy of the nasal mucosa.

Influence on the ability to drive vehicles, machinery

After long-term use of rhinitis remedies containing oxymetazoline in doses higher than recommended, the overall effect on the cardiovascular system and the central nervous system cannot be excluded. In these cases, caution is recommended when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and rapid psychomotor reactions.

Contraindications

• High sensitivity to the components of the drug;
• atrophic (dry) rhinitis;
• taking monoamine oxidase inhibitors during the previous 2 weeks and within 2 weeks after their withdrawal;
• closed angle glaucoma;
• surgical interventions on the dura mater (history);
• condition after transsphenoidal pituitaryectomy;