Sanorin with menthol and eucalyptus, spray 0.1% 10 ml

Pharmacotherapeutic group: Antinoconstrictive agent – alpha-adrenomimetic.< br>

Pharmacodynamics

Nafazolin is an alpha-adrenergic stimulant with fast, expressed and prolonged vasoconstrictor effect against the vessels of mucous membranes of the nasal cavity, nasopharynx and accessory sinuses – it reduces swelling, hyperemia and exudation improving nasal passageway patency and facilitating nasal breathing. At the same time the patency of the eustachian tubes is restored.< br>

Therapeutic effect usually comes within 5 minutes after the introduction of the drug and lasts for 4-6 hours. Tolerance occurs after 5-7 days.< br> The menthol and eucalyptol contained in the drug have a cooling effect on the nasal mucosa giving a feeling of freshness.

Pharmacokinetics

When used topically, systemic absorption is low. The vasoconstrictor effect occurs within a few minutes and lasts for several hours.

Indications

Acute rhinitis (including against the background of acute respiratory diseases and allergic rhinitis), sinusitis, eustachitis, laryngitis, laryngeal edema of allergic genesis, laryngeal edema against irradiation, mucosal hyperemia after operations on the upper respiratory tract.

To stop nasal bleeding.

To facilitate rhinoscopy.

Active ingredient

Nafazolin

Composition

Composition of the drug per 1 ml:

Active ingredient:

Nafazoline nitrate 1.0 mg

Excipients:

Boric acid 16.0 mg

Liquid sorbitol (non-crystallizing) 14.0 mg

Macrogol glycerylhydroxystearate 2.5 mg

Levomenthol 0.3 mg

Cineol (eucalyptol) 0.2 mg

Water for injection up to 1 ml.

How to take, the dosage

Intranasally (into each nasal passage) adults are prescribed 1-3 injections 3-4 times a day. Immediately after injection it is recommended to make light nasal breathing.

For diagnostic purposes – after cleaning the nose into each nasal passage to inject once or insert a sponge soaked in the drug solution and leave for 1-2 minutes.

Use for a short time, but not more than 1 week. If nasal breathing becomes easier, the drug can be terminated earlier. Repeated use of the drug is possible after a few days.

Interaction

It should not be used simultaneously with monoamine oxidase inhibitors or within 14 days after the end of their use.

Delays the absorption of local anesthetic drugs (prolongs their effect during surface anesthesia).

Special Instructions

It may cause resorptive action.

In case of long-term use the vasoconstrictor effect is gradually reduced (tachyphylaxis phenomenon). In this regard it is recommended to make a break for a few days after 5-7 days of use.

In view of the possible development of side effects of the cardiovascular and nervous system the drug doses recommended for use should not be exceeded.

Avoid getting the drug in the eyes.

The drug should be used individually in order to avoid the spread of infection.

Contraindications

Hypersensitivity to the components of the drug, arterial hypertension, marked atherosclerosis, hyperthyroidism, severe eye disease, closed-angle glaucoma, chronic rhinitis, atrophic rhinitis, childhood under 18 years, diabetes, tachycardia, simultaneous use of monoamine oxidase inhibitors and period up to 14 days after their end use.

With caution

Ischemic heart disease (angina pectoris), prostatic hyperplasia, pheochromocytoma, pregnancy, breast-feeding period.

Side effects

Nausea, tachycardia, headache, increased blood pressure, reactive hyperemia, nasal mucosa swelling, irritation, if used for more than 1 week – nasal mucosa edema, atrophic rhinitis.

Overdose

Symptoms: decreased body temperature, bradycardia, increased blood pressure.

Treatment: symptomatic.

Pregnancy use

Use for the treatment of pregnant women and during breastfeeding is possible only if the expected benefit to the mother exceeds the potential risk to the fetus and child.

Similarities

Naphtisin, Naphtisin Renewal