Piroxicam, 10 mg capsules 20 pcs

Pyroxicam is an analgesic, antipyretic, anti-inflammatory.

Selectively inhibits cyclooxygenase, disrupts the metabolism of arachidonic acid, reduces the formation of GH.

Allows or eliminates pain of moderate intensity, reduces the severity of inflammation, in joint syndrome reduces morning joint stiffness, helps to increase range of motion. Full therapeutic effect is seen after 10-14 days of application.

Indications

Rheumatoid arthritis, osteoarthritis, spondylitis, acute attack of gout, inflammatory diseases of the musculoskeletal system.

Pharmacological effect

Piroxicam is an analgesic, antipyretic, anti-inflammatory.

Selectively inhibits cyclooxygenase, disrupts the metabolism of arachidonic acid, and reduces the formation of PG.

Relieves or eliminates pain of moderate intensity, reduces the severity of inflammation, in case of articular syndrome, reduces morning stiffness of joints, helps to increase range of motion. The full therapeutic effect appears after 10–14 days of use.

Special instructions

Patients with gastrointestinal dysfunction, after extensive surgical interventions, in old age, patients with bronchial asthma and a history of chronic bronchospastic diseases need to monitor the cellular composition of the blood, kidney and liver function.

In women, the contraceptive effect of an IUD may be reduced due to the effect of piroxicam on myometrial tone. Recommendations for use in children have not yet been developed. During treatment, the use of ethanol should be avoided.

Should not be applied to damaged skin. Avoid contact with eyes or mucous membranes.

During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Active ingredient

Piroxicam

Composition

Active ingredient:

pyroxekam

Pregnancy

Piroxicam is contraindicated for use during pregnancy and lactation.

Contraindications

Hypersensitivity, incl. to NSAIDs, peptic ulcer, hematopoietic disorders, liver and kidney diseases, cardiovascular failure, bronchial asthma, pregnancy, breastfeeding (breastfeeding should be suspended).

Side Effects

Erosive and ulcerative lesions of the gastrointestinal tract, swelling, headache, dizziness, drowsiness, allergic skin reactions.

Interaction

Enhances the effect of oral anticoagulants, increases the concentration of lithium salts in the blood.

Alcohol increases the likelihood of side effects.

Blood levels are reduced by salicylic acid derivatives.

Overdose

Symptoms: nausea, vomiting (at high doses – bloody), melena, Meniere-like phenomena, tinnitus, clonic and tonic convulsions, coma, hemorrhagic diathesis, agranulocytosis, aplastic anemia, petechial or bullous rash, urticaria, measles or typhus-like rashes; in predisposed patients – toxic-allergic shock.

Treatment: carried out according to generally accepted principles of clinical toxicology.

Storage conditions

In a dry place, protected from light, at a temperature not exceeding 25 °C

Shelf life

2 years

Manufacturer

Sopharma JSC, Bulgaria