Phenibut, tablets 250 mg 20 pcs

Phenibut is a nootropic medicine.

Removes tension, anxiety and fear, improves sleep. It prolongs the latent period and shortens the duration and severity of nystagmus, has an antiepileptic effect.

Limits manifestations of asthenia and vasovetegetative symptoms, including headache, feeling of heaviness in the head, sleep disturbance, irritability, emotional lability, increases mental performance. Improves psychological parameters: attention, memory, speed and accuracy of sensory-motor reactions.

Patients from the first days of therapy feel better, interest and initiative, motivation of activity are increased.
Phenibut administration after severe traumatic brain injury increases the number of mitochondria in perifocal areas and improves bioenergetic processes in the brain.

Phenibut also has an antioxidant effect.

When used in the elderly, Phenibut does not cause congestion and excessive lethargy.
It normalizes the processes of lipid peroxidation. Does not affect the choline and adrenoreceptors.

Indications

Irritability, Anxiety, Neurosis, Aggressiveness and conflict, Insomnia, Asthenia, Enuresis, Hangover, Meniere’s disease, motion sickness, Alcoholism

• Asthenic and anxiety-neurotic states, anxiety, fear, obsessive neurosis, psychopathy.
• Stuttering and tics in children, enuresis.
• Myelodysplasia urinary retention.
• Elderly insomnia and nightmares.
• Prevention of anxiety that occurs before surgical procedures and painful diagnostic tests (premedication).
• Meniere’s disease, vertigo, associated with dysfunctions of the vestibular analyzer of various genesis (including otogenic labyrinthitis, vascular and traumatic disorders); prevention of motion sickness in kinetosis.
• Primary open-angle glaucoma (as part of combination therapy).
• Auxiliary therapy in alcoholism treatment (for regulation of psychopathological and somatovegetative disorders in withdrawal syndrome).
• Treatment of pre-delirium and delirium states in alcoholism (in combination with standard detoxification means).
  

Active ingredient

Aminophenyl butyric acid

Composition

1 tablet contains:

the active ingredient:

γ-amino-β-phenylbutyric acid hydrochloride 250 mg

How to take, the dosage

Phenibut is used orally before meals, for a course of 4-6 weeks.

Adults are prescribed in an average dose of 250-500 mg 3 times a day; if necessary, the dose is increased to 2.5 g/day. The maximum single dose is 750 mg, for people over 60 years old 500 mg.

For children from 2 to 8 years old – 50-100 mg 3 times/day, maximum single dose – 150 mg; for children 8-14 years old – 250 mg 3 times/day, maximum single dose – 300 mg.

To relieve alcohol withdrawal syndrome in the first days of therapy, the drug is prescribed for 250-500 mg 3 times a day and 750 mg at night, with gradual reduction of the daily dose to the usual for adults.

In otogenic labyrinthitis and Meniere’s disease during exacerbation – 750 mg 3-4 times a day for 5-7 days, when the severity of vestibular disorders decreases – 250-500 mg 3 times a day for 5-7 days and then 250 mg once a day for 5 days. In a mild course of the disease, 250 mg 2 times a day for 5-7 days, with subsequent reduction of the dose to 250 mg once a day for 7-10 days.

For the treatment of vertigo in disorders of the vestibular system of vascular and traumatic genesis – 250 mg 3 times a day for 12 days.

For prevention of motion sickness – 250-500 mg once 1 hour before the intended trip (the effect is dose-dependent).

Interaction

When used together, Phenibut prolongs and enhances the effects of hypnotics, neuroleptics, anticonvulsants and opioid analgesics.

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Special Instructions

The drug is prescribed with caution in erosive-ulcerative lesions of the gastrointestinal tract.

Long-term use requires monitoring of liver function parameters and peripheral blood count.

Impact on driving and operating machinery

Potentially dangerous activities requiring increased attention should be avoided.

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Contraindications

• individual intolerance to Phenibut
• pregnancy
• breast-feeding period
• hepatic failure.

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Side effects

CNS disorders: increased irritability, agitation, anxiety, dizziness, headache, drowsiness.

Digestive system disorders: nausea (in the first administration).

Allergic reactions: skin rash, itching.

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Overdose

Symptoms: drowsiness, nausea, vomiting, arterial hypotension, renal failure. When prolonged use of Phenibut at a daily dose of 7-14 g the development of hepatotoxic effects (including fatty liver dystrophy), eosinophilia is possible.

Treatment: gastric lavage, symptomatic and supportive therapy.

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Similarities

Noofen, Anvifen