Pagluferal 2, tablets 20 pcs

Epilepsy, SeizuresEpilepsy.

Indications

Epilepsy.

Pharmacological effect

Combined antiepileptic drug.

Special instructions

In patients with mild hypercalciuria, decreased glomerular filtration, or a history of nephrolithiasis, the drug should be prescribed under the control of calcium levels in the urine, which is due to the presence of calcium gluconate in the drug.

Active ingredient

Bromizoval, Calcium gluconate, Caffeine, Papaverine, Phenobarbital

Composition

Composition per tablet

Phenobarbital
– 0.035 g
Bromized
– 0.1 g
Caffeine sodium benzoate
– 0.0075 g
Papaverine hydrochloride
– 0.015 g
Calcium gluconate
– 0.25 g
Excipients
Potato starch
– 0.0784 g
Calcium stearate
– 0.0041 g

Contraindications

Hypersensitivity to any of the components of the drug, severe liver and/or renal failure, drug dependence (including a history), hyperkinesis, myasthenia gravis, severe anemia, porphyria, diabetes mellitus, hypoadrenal function, hyperthyroidism, depression, broncho-obstructive diseases, active alcoholism, pregnancy, lactation.

This dosage form is not used in children under 3 years of age.

With caution: in weakened patients (high risk of paradoxical agitation, depression and confusion, even when prescribed normal doses).

Side Effects

Dizziness, general weakness, ataxia, dysarthria, nystagmus, paradoxical reaction (especially in elderly and weakened patients – agitation), hallucinations, sleep disturbances, nausea, vomiting, constipation or diarrhea, increased activity of liver transaminases, agranulocytosis, megaloblastic anemia, thrombocytopenia, decreased or increased blood pressure, tachycardia, arrhythmia (including extrasystole), atrioventricular block, allergic reactions, with long-term use – drug dependence.

Interaction

Phenytoin and valproate increase the content of phenobarbital in the blood serum.

Overdose

Symptoms: increased severity of side effects.

Storage conditions

List B. In a dry place, protected from light and out of reach of children, at temperatures above 25 °C.

Shelf life

2 years.

Manufacturer

Moscow pharmaceutical factory, Russia