Otrivin Children’s Spray 0.05% 10 ml

A vasoconstrictor for local use in ENT practice (decongestant). Xylometazoline has an alpha-adrenomimetic effect. Causes narrowing of blood vessels of nasal mucosa, eliminating edema and hyperemia of nasopharyngeal mucosa. It relieves nasal breathing in rhinitis.

Otrivin® is well tolerated by patients with sensitive mucous membranes, its effect does not prevent mucus secretion. The drug has a balanced pH-value typical for nasal cavity.

The composition of the drug includes inactive components – sorbitol and hypromellose that are humectants, reducing symptoms of irritation and dry nasal mucosa which occur after long-term use of xylometazoline.

In therapeutic concentrations the drug does not irritate the mucous membrane and does not cause hyperemia.

The action comes in 2 minutes after application and lasts for 12 hours.

In vitro studies have shown that in humans xylometazoline suppresses the infectious activity of rhinovirus that causes “colds”.

Indications

Acute respiratory diseases with rhinitis symptoms; Acute allergic rhinitis; pollinosis; sinusitis; eustachian sinusitis; otitis media (to reduce nasopharyngeal mucous membrane edema); preparing a patient for diagnostic manipulations in the nasal passages.

Active ingredient

Composition

1 ml:

– xylometazoline hydrochloride 500 mcg

Excipients:

Sodium dihydrophosphate dihydrate – 5 mg,

Sodium hydrophosphate dodecahydrate – 1.7 mg,

dinatrium edetate – 500 µg,

benzalkonium chloride (in the form of 50% solution) – 100 µg,

sorbitol 70% – 20 mg,

hypromellose-4 thousand. – 5 mg

sodium chloride – 4 mg,

purified water – up to 1 ml.

How to take, the dosage

Interaction

Incompatible with MAO inhibitors and tricyclic antidepressants.

Special Instructions

Synopsis

Contraindications

Hypersensitivity to the components of the drug; arterial hypertension; tachycardia; marked atherosclerosis; glaucoma; atrophic rhinitis; hyperthyroidism; brain surgery (in anamnesis); children under 6 years (for 0.1% spray).

With caution, use in patients with diabetes mellitus, cardiovascular disease, hypersensitivity to adrenergic drugs, accompanied by symptoms of insomnia, dizziness, cardiac arrhythmia, tremor, high BP.

Side effects

Overdose

Pregnancy use

Similarities