Ondansetron-Altfarm, rectal 16 g mg 2 pcs

How to take, the dosage

The drug is used rectally. To remove the suppository from the cell pack, break off one cell with the suppository along the notch and pull the edges of the tape apart in different directions. The suppository is inserted into the anus with the pointed end, as deep as possible. For more comfortable insertion of the suppository is recommended to bend over, squat or lie on your side with your legs tucked. The choice of dosing regimen is determined by the severity of the emetogenic effect of the antitumor therapy.

In moderate emetogenic chemotherapy or radiotherapy:
– 16 mg ondansetron 1-2 hours before the beginning of basic therapy.

For highly emetogenic chemotherapy:
The recommended dose is 16 mg simultaneously with intravenous infusion of 20 mg dexamethasone 1-2 hours before the start of chemotherapy.
To prevent late or prolonged vomiting occurring 24 hours after the end of chemotherapy or radiotherapy, the drug should be continued in a dose of 16 mg once daily for 5 days. The drug is used rectally. To remove the suppository from the cellular package, you should break off one cell with a suppository on a notch and separating the edges of the tape, pulling them in different directions. The suppository is inserted into the anus with the pointed end, as deep as possible. For more comfortable insertion of the suppository is recommended to bend over, squat or lie on your side with your legs tucked. The choice of dosing regimen is determined by the severity of the emetogenic effect of the antitumor therapy.

In moderate emetogenic chemotherapy or radiotherapy:
– 16 mg ondansetron 1-2 hours before the beginning of basic therapy.

For highly emetogenic chemotherapy:
The recommended dose is 16 mg simultaneously with intravenous infusion of 20 mg dexamethasone 1-2 hours before the start of chemotherapy.
To prevent late or prolonged vomiting occurring 24 hours after the end of chemotherapy or radiotherapy, the drug should be continued at a dose of 16 mg once daily for 5 days.

Contraindications

Hypersensitivity, childhood – for rectal administration (up to 2 years old – for oral and parenteral administration).

Side effects

Gastrointestinal system disorders: constipation/diarrhea, dry mouth, hiccups, transient increase in AST and ALT levels.

Nervous system and sensory organs: headache, dizziness, spontaneous motor disorders and seizures, visual acuity disorders, extrapyramidal disorders (in parenteral use).

Cardiovascular and blood (hematopoiesis, hemostasis): syncope, chest pain, in some cases with ST-segment depression, bradycardia, arrhythmia, arterial hypotension.

Allergic reactions: urticaria, bronchospasm, laryngospasm, angioedema, anaphylaxis.

Others: fever, sensation of heat, blood rush to the face, hypokalemia, hypercreatinemia, local reactions (pain, redness and burning at the injection site); burning in the anus and rectum (suppositories).

Similarities

Latran, Ondansetron