OKI, 150 ml
€22.10 €18.41
Pharmacotherapeutic group
Other oral medications.
TAC code: A01AD11.
Pharmacodynamics
It has anti-inflammatory, analgesic effects. By inhibiting cyclooxygenase types I and II, inhibits the synthesis of inflammatory mediators (prostaglandins, thromboxane, etc.). Stabilizes lysosomal membranes and inhibits the release of enzymes that contribute to tissue destruction during inflammation. Inhibits the activity of neutrophils. It has anti-bradykinin activity. The drug does not have antibacterial activity.
Pharmacokinetics
A single dose of 160 mg results in plasma levels of less than 400 ng/mL, insufficient for systemic action.
Indications
Periodontal disease, Colds, Tonsillitis, Pain, Gum inflammation, Stomatitis, Laryngitis, Sore throat, Angina, Pharyngitis
Symptomatic treatment of inflammatory diseases of the upper respiratory tract – tonsillitis (angina), laryngitis, pharyngitis;
inflammatory diseases of the oral cavity – stomatitis, gingivitis, glossitis, aphthae, periodontopathy, chronic periodontal disease;
as an analgesic agent during dental manipulations.
Active ingredient
Ketoprofen
Composition
Active ingredients:
- ketoprofen lysine (ketoprofen lysine salt) 160.0 mg.
Auxiliary substances:
- glycerol 85% 2000.0 mg,
- ethanol 0.5 ml,
- mint flavoring 30.0 mg,
- levomenthol 7.0 mg,
- Sodium saccharinate 20.0 mg,
- dye Verde chertosa (brilliant green) 1.6 mg,
- Sodium hydrophosphate to pH 6.0-6.5,
- water purified to 10 ml.
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How to take, the dosage
Two rinses per day, 10 ml of the solution at a time.
10 ml of the solution should be measured with the measuring cup included in the package and diluted in 100 ml (half a cup) of drinking water.
To open the bottle, firmly press the top of the cap and turn it counterclockwise. Firmly screw the cap back on after use.
Inadvertent swallowing of the solution does not have serious consequences, because the single rinse dose contains 160 mg of ketoprofen lysine, which is the same as the oral dose.
Special Instructions
Prolonged use may cause hypersensitivity reactions. In this case, the drug should be discontinued and adequate treatment methods should be chosen.
When using high doses and long-term treatment the absorbable ketoprofen may compete with other drugs that have high affinity for plasma proteins.
The drug contains methyl parahydroxybenzoate, which may cause allergic reactions (including delayed-type allergic reactions).
Influence on driving and operating machinery
There are no data of adverse effects of the drug on the ability to drive vehicles and engage in other potentially dangerous activities requiring concentration and quick psychomotor reactions.
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Contraindications
Hypersensitivity to ketoprofen and other components of the drug, acetylsalicylic acid or other NSAIDs, complete or incomplete combination of bronchial asthma, recurrent polyposis of the nose or sinuses and intolerance to acetylsalicylic acid and other NSAIDs (including history), childhood (under 12 years), pregnancy over 20 weeks.
With caution
gastrointestinal erosive ulcers (exacerbation), Crohn’s disease, diverticulitis, peptic ulcers, hemophilia and others. blood clotting disorders, chronic heart failure, bronchial asthma, advanced age, pregnancy (up to the 20th week).
Side effects
Very rare cases of local irritation and angioedema (swelling of the lips, face, throat or tongue) have been reported, especially in patients with hypersensitivity to NSAIDs. Cases of systemic side effects are unknown.
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Overdose
There are currently no reported cases of overdose with OCI.
Pregnancy use
Women should not use NSAIDs from the 20th week of pregnancy due to the possible development of oligo and/or renal abnormalities in the newborn (neonatal renal dysfunction). The use of the drug before the 20th week of pregnancy is possible only after consultation with a physician, if the expected benefits to the mother exceed the potential risk to the fetus.
The use of the drug during breastfeeding is not recommended.
Similarities
Ketonal, OKI, Bystromgel, Febrofid, Flamax forte, Ketoprofen, Flamax, Fastum, Rocketal Rompharm, Pentalgin extra-gel, Ketonal DUO, Ketoprovel, OKI ACT, Brustel
Weight | 0.230 kg |
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Shelf life | Shelf life 3 years. Do not use the drug after the date shown on the package. |
Conditions of storage | Store at temperatures under 25 oC. Keep out of reach of children! |
Manufacturer | Dompe Pharmaceutici S.p.A., Italy |
Medication form | gargle solution |
Brand | Dompe Pharmaceutici S.p.A. |
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