Nystatin, rectal 500000 units 10 pcs

Nystatin is fungistatic.

Binding with sterols in the cell wall of fungi, it violates its permeability, which leads to the release of the main components of the cell.

It is active against yeast-like fungi of the genus Candida, including Candida albicans. It does not have cumulative properties.

Pharmacokinetics

Poorly absorbed from the gastrointestinal tract.

The bulk of the drug taken orally is excreted in the feces. It is not absorbed through the mucous membranes when administered topically.

Indications

candidiasis of the lower intestine;
prevention of fungal infections in the pre- and postoperative periods.

Pharmacological effect

Nystatin is fungistatic.

By binding to sterols in the cell wall of fungi, it disrupts its permeability, which leads to the release of the main components of the cell.

Active against yeast-like fungi of the genus Candida, incl. Candida albicans. Does not have cumulative properties.

Pharmacokinetics

Poorly absorbed from the gastrointestinal tract.

The bulk of the drug taken orally is excreted in the feces. When applied topically, it is not absorbed through the mucous membranes.

Active ingredient

Nystatin

Composition

Active ingredients:

nystatin 500,000 units

Excipients:

propyl ester of parahydroxybenzoic acid,

food grade citric acid,

Vaseline oil,

vitepsol N-15,

vitepsol W-35.

Contraindications

liver dysfunction;
pancreatitis;
peptic ulcer of the stomach and duodenum;
pregnancy;
hypersensitivity to the components of the drug.

Side Effects

From the digestive system: when taking the drug orally and using rectal suppositories, nausea, vomiting, and diarrhea are possible.

Allergic reactions: skin itching, chills, fever.

Other: there may be a risk of the spread of resistant forms of fungi, which requires discontinuation of the drug.

Storage conditions

In a dry place, protected from light, at a temperature not exceeding 5 °C

Shelf life

2 years

Manufacturer

Biosynthesis, Russia