Nasivin, spray 22.5 mcg/dose 10 ml

Nasal congestion, Sinusitis, Otitis, Colds, Allergic rhinitis, Pollinosis, Sneezing, runny nose (rhinitis)

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Indications

Colds or viral infections of the upper respiratory tract, accompanied by a runny nose;
Rhinitis of any etiology;
Sinusitis;
Eustachite;
Otitis media;
To eliminate swelling before diagnostic manipulations in the nasal passages.

Pharmacological effect

Vasoconstrictor drug for local use.

Special instructions

Avoid contact of the drug with the eyes.

To avoid the spread of infection, it is necessary to use the drug individually.

Impact on the ability to drive vehicles and operate machinery

After long-term use of cold remedies containing oxymetazoline in doses higher than recommended, a general effect on the cardiovascular system and central nervous system cannot be excluded. In these cases, patients should be careful when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Active ingredient

Oxymetazoline

Composition

1 dose of the drug (45 µl) contains:

Pregnancy

When used during pregnancy or breastfeeding, do not exceed the recommended dosage.

Contraindications

Atrophic rhinitis;
Angle-closure glaucoma;
Children under 1 year of age (for the drug Nazivin® Sensitive nasal spray dosed 11.25 mcg/dose);
Children under 6 years of age (for the drug Nazivin® Sensitive nasal spray dosed 22.5 mcg/dose);
Hypersensitivity to the components of the drug.

The drug should be used with caution in patients with increased intraocular pressure, chronic heart failure, arterial hypertension, angina pectoris, arrhythmia, chronic renal failure, in patients with prostatic hyperplasia with clinical symptoms (urinary retention), severe atherosclerosis, hyperthyroidism, diabetes mellitus, pheochromocytoma, as well as in patients who have received MAO inhibitors within the previous 2 weeks and in within 2 weeks after their withdrawal, tricyclic antidepressants, bromocriptine.

Side Effects

Local reactions:

from ≥1% to <10% - burning or dryness of the nasal mucosa, sneezing, a strong feeling of nasal congestion (reactive hyperemia) after the effect of using the drug Nazivin® Sensitive wears off, blurred vision (if it gets into the eyes). Long-term continuous use of vasoconstrictor drugs can lead to tachyphylaxis, atrophy of the nasal mucosa and recurrent swelling of the nasal mucosa (rhinitis medicamentosa).

From the cardiovascular system:

from ≥0.1% to <1% - increased blood pressure, tachycardia; perhaps a feeling of heartbeat.

From the nervous system:

from ≥0.01% to <0.1% - headache, insomnia; possible - dizziness, anxiety, irritability, sleep disturbance (in children).

Other:

Possibly nausea, exanthema.

Interaction

The drug slows down the absorption of local anesthetic drugs and prolongs their effect.

When using the drug Nazivin® Sensitive for 2 weeks before prescribing MAO inhibitors and for 2 weeks after their discontinuation, during treatment with tricyclic antidepressants or other drugs that increase blood pressure, an increase in blood pressure is observed.

Co-administration of other vasoconstrictor drugs increases the risk of side effects.

Overdose

Symptoms: nausea, increased blood pressure, tachycardia, central nervous system depression.

Treatment: symptomatic therapy.

Storage conditions

The drug should be stored out of the reach of children at a temperature not exceeding 30°C.

Shelf life

3 years.

Manufacturer

Sofarimex Industria Kimica e Pharmasuetica S.A., Portugal