Mycoderil, cream 1% 30 g
€21.93 €18.27
Pharmacodynamics
Naftifin is an antifungal agent for external use, belonging to the class of allilamines. The mechanism of action is related to inhibition of squalene-2,3-epoxidase, which leads to reduction of formation of ergosterol, which is a part of the cell wall of the fungus. It is active against dermatophytes such as Trichophyton, Epidermophyton and Microsporum, molds (Aspergillus spp.), yeasts (Candida spp., Pityrosporum) and other fungi (such as Sporothrix schenckii).
With respect to dermatophytes and aspergillus naphthifin acts fungicidal. Against yeast fungi the drug has fungicidal or fungistatic activity depending on the strain of the microorganism. It has antibacterial activity against Gram-positive and Gram-negative microorganisms that can cause secondary bacterial infections. It has anti-inflammatory action, which contributes to the rapid disappearance of symptoms of inflammation, especially itching.
Pharmacokinetics
When applied topically, it penetrates well into various layers of the skin, creating stable antifungal concentrations in its various layers. After application on the skin less than 6% of naphthifin is absorbed systemically. Absorbed amount is partially metabolized and excreted by kidneys and intestine. Half-life period of the drug is 2 – 3 days.
Indications
– Fungal infections of smooth skin and skin folds (tinea corporis, tinea inquinalis);
– interfinger mycoses (tinea manum, tinea pedum);
– fungal infections of the nails (onychomycoses);
– candidiasis of the skin;
– peptic ulcer;
– dermatomycoses (with or without itching).
Active ingredient
Composition
1 g of the cream: the active ingredient:
naphthyphine hydrochloride – 10 mg;
additional components:
isopropyl myristate – 80 mg,
cetostearyl alcohol – 80 mg,
How to take, the dosage
Externally.
In case of skin lesions Mikoderil is applied 1 time/day on the affected skin surface and adjacent areas after thorough cleaning and drying (covering about 1 cm of healthy skin area at the edges of the affected area).
The duration of therapy in dermatomycosis is 2-4 weeks (up to 8 weeks if necessary), in candidiasis – 4 weeks.
In case of nail lesions Mikoderil is applied 2 times a day on the affected nail. Before the first use, remove the affected part of the nail with scissors or a nail file as much as possible.
The duration of therapy for opichomycosis is up to 6 months.
To prevent a relapse, treatment should be continued for at least 2 weeks after clinical symptoms have disappeared.
Interaction
Special Instructions
Contraindications
– Hypersensitivity to naphthyphine, benzyl alcohol or other components of the drug;
– pregnancy and lactation (safety and effectiveness of the drug in this category of patients has not been studied).
With caution: childhood (clinical experience is limited).
Side effects
Pregnancy use
Similarities
Weight | 0.047 kg |
---|---|
Shelf life | 2 years if the manufacturer's recommendation is followed |
Conditions of storage | Storage temperature not more than 25 ° C.. |
Manufacturer | Lekko ZAO, Russia |
Medication form | exterior cream |
Brand | Lekko ZAO |
Other forms…
Related products
Buy Mycoderil, cream 1% 30 g with delivery to USA, UK, Europe and over 120 other countries.