Mycoderil, 1% 30 ml
€34.58 €28.81
Pharmacotherapeutic group: antifungal agent.
The ATX code: D01AE22
Pharmacological properties
Pharmacodynamics
Mycoderil®, topical solution, 1% is an antifungal agent for external use, belonging to allilamines class. Its active ingredient is naphthifine. The mechanism of action is associated with inhibition of squalene-2,3-epoxidase, which leads to a decrease in the formation of ergosterol, which is part of the cell wall of the fungus. Naftifine, affecting squalene epoxidase, does not affect the cytochrome P-450 system.
Naftifine is active against dermatophytes such as Trichophyton, Epidermophyton, Microsporum, yeast and yeast-like fungi (Candida spp., Pityrosporum), molds (Aspergillus) and other fungi (such as Sporothrix schenckii). Against dermatophytes and aspergillus naphthifin acts fungicidal. Against yeast fungi the drug has fungicidal or fungistatic activity depending on the strain of the microorganism. Naftifin has antibacterial activity against Gram-positive and Gram-negative microorganisms causing secondary bacterial infections.
Naftifine has anti-inflammatory properties that help to quickly disappear the symptoms of inflammation, especially itching.
Pharmacokinetics
When used topically, naphthifin quickly penetrates the skin, creating sustained antifungal concentrations in different layers of the skin, making once-daily use possible.
Indications
Active ingredient
How to take, the dosage
Externally.
In dermatomycosis and candidiasis of the skin.
Mycoderil®, solution for external use, 1% is applied once a day to the affected skin surface and its surroundings after thorough cleaning and drying, covering about 1 cm of healthy skin area at the edges of the affected area. Duration of treatment: in dermatomycosis 2-4 weeks (if necessary up to 8 weeks), in candidiasis – 4 weeks.
In lesions of the nails (onychomycosis).
Before the first use of the drug, remove the affected part of the nail with scissors and a nail file as much as possible. The drug is used 2 times a day, the duration of treatment for onychomycosis is up to 6 months. To prevent recurrence of the infection the drug should be continued for at least 2 weeks after the disappearance of clinical symptoms.
Special Instructions
Mycoderil®, a solution for external use, 1% is effective in the treatment of mycoses affecting areas of the skin with hyperkeratosis, as well as in areas of hair growth.
Course treatment is required.
Contact of the drug in the eyes and on open wounds should be avoided.
Pediatric use
The drug should be used with caution in children.
Mycoderil®, topical solution, 1% has no adversebr> affect the ability to drive vehicles and perform other activities requiring concentration and quick psychomotor reactions.
Contraindications
Hypersensitivity to naphthyphine or propylene glycol; pregnancy and lactation (safety and effectiveness of the drug in this category of patients has not been studied).
Application of the drug on the wound surface is contraindicated.
Childhood (clinical experience limited).
Side effects
Pregnancy use
Similarities
Weight | 0.084 kg |
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Shelf life | 2 years. Do not use after the expiration date printed on the package. |
Conditions of storage | Store at a temperature not exceeding 25 oC. Keep out of reach of children. |
Manufacturer | Pharmstandard-Leksredstva, Russia |
Medication form | solution for external use |
Brand | Pharmstandard-Leksredstva |
Other forms…
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