Mycoderil, 1% 20 ml

Mycoderil^® is an antifungal drug for external use, the active ingredient of which is naphthifine. Naphtifine is an antifungal agent belonging to the class of alilamines. The mechanism of action is associated with inhibition of squalene-2,3-epoxidase, which leads to a decrease in the formation of ergosterol, which is part of the cell wall of the fungus. Naftifine, affecting squalene epoxidase, does not affect the cytochrome P-450 system.

Naftifine is active against dermatophytes such as Trichophyton, Epidermophyton, Microsporum, yeast and yeast-like fungi (Candidaspp., Pityrosporum), molds (Aspergillus) and other fungi (such as Srohichryshepensis). Against dermatophytes and aspergillus naphthifin acts fungicidal.

In yeast fungi the drug has fungicidal or fungistatic activity depending on the strain of the microorganism. Naphtifine has antibacterial activity against Gram-positive and Gram-negative microorganisms causing secondary bacterial infections.

Naftifine has anti-inflammatory properties that help to quickly disappear the symptoms of inflammation, especially itching.

Pharmacokinetics

When used topically, naphthifin quickly penetrates the skin, creating sustained antifungal concentrations in different layers of the skin, making once-daily use possible.

Indications

Active ingredient

Composition

How to take, the dosage

Interaction

Special Instructions

Please read the instructions for use carefully before using this medicine because they contain important information for you.

Mycoderil®, a spray for external use, 1% is effective in treating mycoses affecting areas of skin with hyperkeratosis and in areas of hair growth.
A course of treatment is required.
Avoid contact of the drug with eyes and open wounds.
Pediatric use
The drug should be used with caution in children.

Contraindications

Hypersensitivity to naphthyphine or propylene glycol; pregnancy and breastfeeding (safety and effectiveness of the drug in this category of patients has not been studied).
Application of the drug on the wound surface is contraindicated.

Side effects

Overdose

Pregnancy use

Similarities