Miramistin, 0.01% solution 150 ml

Miramistin® has a broad spectrum of antimicrobial action, including hospital strains resistant to antibiotics.

The drug has a pronounced bactericidal effect against Gram-positive (Staphylococcus spp., Streptococcus spp, Streptococcus pneumoniae, etc.), gram-negative (Pseudomonas aeruginosa, Escherichia coli, Klebsiella spp. etc.), aerobic and anaerobic bacteria determined as monocultures and microbial associations, including hospital strains with multiresistance to antibiotics.

It has antifungal effect on ascomycetes of Aspergillus and Penicillium genus, yeasts (Rhodotorula rubra, Torulopsis gabrata etc.) and yeast-like fungi (Candida albicans, Candida tropicalis, Candida krusei, Pityrosporum orbiculare (Malassezia furfur) etc.), dermatophytes (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton schoenleini, Trichophyton violacent, Epidermophyton Kaufman-Wolf, Epidermophyton floccosum, Microsporum gypseum, Microsporum canis, etc.), as well as other pathogenic fungi, in the form of monocultures and microbial associations, including fungal microflora with resistance to chemotherapeutic drugs.

It has antiviral action and is active against complex viruses (herpes viruses, human immunodeficiency virus and others).

Miramistin® is active against sexually transmitted pathogens (Chlamydia spp., Treponema spp., Trichomonas vaginalis, Neisseria gonorrhoeae, etc.).

Effectively prevents infection of wounds and burns. Activates the regeneration processes. Stimulates the protective reactions at the application site by activating the absorptive and digestive function of phagocytes and potentiates the activity of the monocytic-macrophage system. It has a pronounced hyperosmolar activity, as a result of which it stops wound and perifocal inflammation, absorbs purulent exudate, contributing to the formation of a dry crust. It does not damage granulation and viable skin cells and does not suppress marginal epithelization.

It does not have a local irritant and allergic properties.

Pharmacokinetics

When administered topically, the Miramistin has no ability to be absorbed through the skin and mucous membranes.

Indications

For use in surgery, traumatology: – prevention of suppuration and treatment of purulent wounds; — treatment of purulent-inflammatory processes of the musculoskeletal system. For use in obstetrics and gynecology: – prevention and treatment of suppuration of postpartum injuries, wounds of the perineum and vagina, postpartum infections; — prevention and treatment of inflammatory diseases (vulvovaginitis, endometritis). For use in combustiology: – treatment of superficial and deep burns of II and III A degrees; — preparation of burn wounds for dermatoplasty. For use in dermatology, venereology: – treatment and prevention of pyoderma and dermatomycosis, candidiasis of the skin and mucous membranes; — individual prevention of sexually transmitted diseases (including syphilis, gonorrhea, chlamydia, trichomoniasis, genital herpes, genital candidiasis).

For use in urology: – complex treatment of acute and chronic urethritis and urethroprostatitis of specific (trichomoniasis, gonorrhea) and nonspecific nature.

For use in dentistry: – treatment and prevention of infectious and inflammatory diseases of the oral cavity: stomatitis, gingivitis, periodontitis, periodontitis; — hygienic treatment of removable dentures.

For use in otorhinolaryngology: – complex treatment of acute and chronic sinusitis, tonsillitis, laryngitis; — complex treatment of acute pharyngitis and/or exacerbation of chronic tonsillitis in children aged 3 to 14 years.

Pharmacological effect

Miramistin® has a wide spectrum of antimicrobial action, including hospital strains resistant to antibiotics.

The drug has a pronounced bactericidal effect against gram-positive (Staphylococcus spp., Streptococcus spp., Streptococcus pneumoniae, etc.), gram-negative (Pseudomonas aeruginosa, Escherichia coli, Klebsiella spp., etc.), aerobic and anaerobic bacteria, determined in the form of monocultures and microbial associations, including hospital strains with multiresistance to antibiotics.

It has an antifungal effect on ascomycetes of the genus Aspergillus and the genus Penicillium, yeast (Rhodotorula rubra, Torulopsis gabrata, etc.) and yeast-like fungi (Candida albicans, Candida tropicalis, Candida krusei, Pityrosporum orbiculare (Malassezia furfur), etc.), dermatophytes (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton schoenleini, Trichophyton violacent, Epidermophyton Kaufman-Wolf, Epidermophyton floccosum, Microsporum gypseum, Microsporum canis, etc.), as well as other pathogenic fungi, in the form of monocultures and microbial associations, including fungal microflora with resistance to chemotherapy drugs.

It has an antiviral effect and is active against complex viruses (herpes viruses, human immunodeficiency virus, etc.).

Miramistin® acts on pathogens of sexually transmitted diseases (Chlamydia spp., Treponema spp., Trichomonas vaginalis, Neisseria gonorrhoeae, etc.).

Effectively prevents infection of wounds and burns. Activates regeneration processes. Stimulates protective reactions at the site of application, due to the activation of the absorption and digestive functions of phagocytes, potentiates the activity of the monocyte-macrophage system. It has pronounced hyperosmolar activity, as a result of which it stops wound and perifocal inflammation, absorbs purulent exudate, promoting the formation of a dry scab. Does not damage granulations and viable skin cells, does not inhibit marginal epithelialization.

Does not have a local irritant effect or allergenic properties.

Pharmacokinetics

When applied topically, Miramistin does not have the ability to be absorbed through the skin and mucous membranes.

Active ingredient

Benzyldimethyl 3-(myristoylamino)propylammonium chloride monohydrate

Composition

1 l contains:

Active ingredients:

benzyldimethyl-myristoylamino-propylammonium chloride monohydrate 100 mg.

Excipients:

purified water – up to 1 liter.

Contraindications

Individual intolerance to the drug.

Side Effects

In some cases, a slight burning sensation may occur at the injection site, which goes away on its own after 15–20 seconds and does not require discontinuation of the drug.

Allergic reactions.

Interaction

When used simultaneously with antibiotics, an increase in their antibacterial and antifungal properties was noted.

Storage conditions

At a temperature not exceeding 25 °C.

Shelf life

3 years

Manufacturer

Infamed K, Russia