Ketoprofen-Lor, 16 mg/ml 200 ml

It has anti-inflammatory, analgesic effect. By inhibiting cyclooxygenase type I and II, inhibits the synthesis of inflammatory mediators (prostaglandins, thromboxane, etc.). Stabilizes lysosomal membranes and inhibits the release of enzymes that contribute to tissue destruction during inflammation. Inhibits the activity of neutrophils. It has anti-bradykinin activity.

The drug has no antibacterial action.

Pharmacokinetics

A single dose of 160 mg leads to a plasma level of less than 400 ng/ml, insufficient for systemic action.

Indications

Symptomatic treatment of inflammatory diseases of the upper respiratory tract – tonsillitis (sore throat), laryngitis, pharyngitis; inflammatory diseases of the oral cavity: stomatitis, gingivitis, glossitis, aphthae, periodontopathy, chronic periodontal disease; as an analgesic during dental procedures.

If necessary, please consult your doctor before using the medicine.

Pharmacological effect

Has anti-inflammatory, analgesic effect. By inhibiting cyclooxygenase types I and II, it inhibits the synthesis of inflammatory mediators (prostaglandins, thromboxane, etc.). Stabilizes lysosome membranes and delays the release of enzymes that contribute to tissue destruction during inflammation. Inhibits the activity of neutrophils. Has anti-bradykinin activity.

The drug does not have an antibacterial effect.

Pharmacokinetics

A single dose of 160 mg results in a plasma drug level of less than 400 ng/ml, which is insufficient for systemic action.

Special instructions

Long-term use may cause hypersensitivity reactions.

In this case, you should stop using the drug and select adequate treatment methods.

When using high doses and a long course of treatment, absorbed ketoprofen can compete with other drugs that have a high affinity for plasma proteins.

The drug contains methyl parahydroxybenzoate, which can cause allergic reactions (including delayed allergic reactions).

Read the instructions carefully before you start using the drug. Save the instructions, you may need them again. If you have any questions, consult your doctor. The medicine you are being treated with is intended for you personally and should not be given to others as it may cause harm to them even if they have the same symptoms as you.

Impact on the ability to drive vehicles and machinery

The drug does not affect the ability to drive or engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Active ingredient

Ketoprofen

Composition

Active ingredient:

ketoprofen lysine salt – 16.0 mg.

Excipients:

glycerin – 200.0 mg,

ethanol (ethyl alcohol 95%) in terms of absolute alcohol – 40.0 mg (37.0 mg),

methyl parahydroxybenzoate (nipagin) – 1.5 mg,

levomenthol (L-menthol) – 0.70 mg,

sodium saccharinate – 2.0 mg,

sodium hydrogen phosphate dodecahydrate – 0.78 mg,

mint flavor – 2.40 mg,

brilliant green – 0.016 mg,

purified water – up to 1 ml.

Pregnancy

The use of the drug in the third trimester of pregnancy is contraindicated.
The use of the drug in the first and second trimesters of pregnancy is possible only after consultation with a doctor, if the expected benefit to the mother outweighs the potential risk to the fetus.
The use of the drug during breastfeeding is not recommended.

Contraindications

Hypersensitivity to ketoprofen and other components of the drug, acetylsalicylic acid or other NSAIDs, complete or incomplete combination of bronchial asthma, recurrent polyposis or paranasal sinuses and intolerance to acetylsalicylic acid and other NSAIDs (including a history), children under 12 years of age.

With caution

Erosive and ulcerative lesions of the gastrointestinal tract (exacerbation), Crohn’s disease, diverticulitis, peptic ulcer, hemophilia and other blood clotting disorders, chronic heart failure, bronchial asthma, old age, pregnancy (I and II trimester).

Side Effects

Allergic reactions.

If any of the side effects indicated in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.

Overdose

When using the drug in accordance with the instructions for use, an overdose is unlikely. Accidental ingestion of the solution does not lead to serious consequences, because a single dose for rinsing contains 160 mg of ketoprofen lysine salt, which corresponds to the dose intended for oral administration.

Storage conditions

Store at a temperature not exceeding 25 °C.
Keep out of the reach of children.

Shelf life

2 years.
Do not use after the expiration date stated on the package.

Manufacturer

Pharmstandard-Leksredstva, Russia