Holitilin, 250 mg/ml 4 ml 3 pcs

Holitiline is a nootropic drug. It is a central cholinostimulant containing 40.5% metabolically protected choline.

It provides synthesis of acetylcholine and phosphatidylcholine in neuronal membranes, improves blood flow and enhances metabolic processes in CNS, activates reticular formation.

It increases linear velocity of blood flow, normalizes spatiotemporal characteristics of spontaneous bioelectrical activity of the brain, regresses focal neurological symptoms and restores consciousness; it positively affects cognitive and behavioral reactions of patients with cerebral vascular diseases (discirculatory encephalopathy and residual effects of circulatory disorders of the brain).

It has preventive and corrective effect on pathogenetic factors of involutional psychorganic syndrome, reduces cholinergic activity.

Stimulates the dose-dependent release of acetylcholine under physiological conditions; participating in the synthesis of phosphatidylcholine (membrane phospholipid), improves synaptic transmission, plasticity of neuronal membranes. It has no effect on the reproductive cycle and has no teratogenic, mutagenic action.

Pharmacokinetics

Dissolution: Choline alphoscerate easily penetrates the blood-brain barrier. It is excreted mainly by the lungs as carbon dioxide (85%) and also by the kidneys and through the intestines (15%).

Indications

In complex therapy for:

Active ingredient

Composition

1 ml of solution for intravenous and intramuscular injection contains:

the active ingredient:

choline alphoscerate polyhydrate (GFH Lipoid 85F) 250 mg;

auxiliary substances:

povidone,

water for injection

How to take, the dosage

The drug is administered intramuscularly in a dose of 1 g (1 ampoule) per day or intravenously slowly in 1 g per day for 15-20 days.

Thereafter it is possible to switch to an oral form of the drug (capsules).

Interaction

Drug interactions of the drug have not been established.

Special Instructions

During treatment, caution should be exercised when driving motor vehicles and engaging in other potentially dangerous activities that require increased concentration and quick psychomotor reactions.

Contraindications

Side effects

Digestive system disorders: constipation, diarrhea, dry oral mucosa, pharyngitis.

Nervous system disorders: headache, drowsiness, insomnia, aggressiveness, anxiety, nervousness, dizziness.

Skin disorders: rash, urticaria.

Others: pain at the site of injection, increased frequency of urination.

Similarities