Hepa-Merz, 500 mg/ml concentrate 10 ml 10 pcs

Hepa-Merz is hepatoprotective.

Pharmacodynamics

Participates in the ornithine cycle of Krebs urea formation (biosynthesis of urea from ammonia). It promotes the production of insulin and STH. Improves detoxification function of the liver, lowers elevated plasma ammonia levels. Improves protein metabolism in diseases requiring parenteral nutrition.

Pharmacokinetics

Dissociates into ornithine and aspartate, which are absorbed in the small intestine by active transport through the intestinal epithelium. It is excreted with the urine through the urea cycle.

Indications

Overeating, Liver cirrhosis, Hepatitis, Liver damage, Alcoholism

• acute and chronic liver diseases accompanied by hyperammonemia;
• hepatic encephalopathy (latent and pronounced), including as part of the treatment of impaired consciousness (precoma or coma.
• parenteral nutrition of patients with protein deficiencies (as a corrective supplement)

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Active ingredient

Ornithine

Composition

Active substance:

ornithine aspartate 5 g;

Supplementary substances:

water for injection – up to 10 ml

How to take, the dosage

Intravenously, usually 20 g (4 ampoules), with hepatic encephalopathy, depending on the severity of the condition, up to 40 g (8 ampoules) per day; maximum infusion rate is 5 g/h.

Contraindications

Severe renal dysfunction (plasma creatinine level 3 mg/100 ml).

Side effects

Rarely – skin reactions, in some cases – nausea, vomiting.