Hepa-Merz, 500 mg/ml concentrate 10 ml 10 pcs

Hepa-Merz is hepatoprotective.

Pharmacodynamics

Participates in the ornithine cycle of Krebs urea formation (biosynthesis of urea from ammonia). It promotes the production of insulin and STH. Improves detoxification function of the liver, lowers elevated plasma ammonia levels. Improves protein metabolism in diseases requiring parenteral nutrition.

Pharmacokinetics

Dissociates into ornithine and aspartate, which are absorbed in the small intestine by active transport through the intestinal epithelium. It is excreted with the urine through the urea cycle.

Indications

acute and chronic liver diseases accompanied by hyperammonemia;
hepatic encephalopathy (latent and severe), incl. as part of complex therapy for disorders of consciousness (precoma or coma);
parenteral nutrition for patients with protein deficiency (as a corrective supplement).

Pharmacological effect

Hepa-Merz – hepatoprotective.

Pharmacodynamics

Participates in the ornithine Krebs urea cycle (biosynthesis of urea from ammonia). Promotes the production of insulin and growth hormone. Improves the detoxification function of the liver, reduces elevated levels of ammonia in plasma. Improves protein metabolism in diseases requiring parenteral nutrition.

Pharmacokinetics

Dissociates into ornithine and aspartate, which are absorbed in the small intestine by active transport through the intestinal epithelium. It is excreted in urine through the urea cycle.

Active ingredient

Ornithine

Composition

Active ingredient:

ornithine aspartate 5 g;

Excipients:

water for injection – up to 10 ml

Contraindications

Severe renal impairment (plasma creatinine level 3 mg/100 ml).

Side Effects

Rarely – skin reactions, in some cases – nausea, vomiting.

Storage conditions

At a temperature not exceeding 25 °C.

Shelf life

3 years

Manufacturer

Merz Pharma GmbH & Co. KGaA, Germany