Hepa-Merz, 5 g 10 pcs

Hepa-Merz is hepatoprotective.

Pharmacodynamics

Participates in the ornithine cycle of Krebs urea formation (biosynthesis of urea from ammonia).

Promotes the production of insulin and STH. It improves the detoxification function of the liver and lowers elevated levels of ammonia in the plasma.

Enhances protein metabolism in diseases requiring parenteral nutrition.

Pharmacokinetics

Dissociates into ornithine and aspartate, which are absorbed in the small intestine by active transport through the intestinal epithelium.

Extracted with the urine through the urea cycle.

Indications

Acute and chronic liver diseases accompanied by hyperammonemia;
hepatic encephalopathy (latent and severe), incl. as part of complex therapy for disorders of consciousness (precoma or coma);
parenteral nutrition for patients with protein deficiency (as a corrective supplement).

Pharmacological effect

Hepa-Merz – hepatoprotective.

Pharmacodynamics

Participates in the ornithine Krebs urea cycle (biosynthesis of urea from ammonia).

Promotes the production of insulin and growth hormone. Improves the detoxification function of the liver, reduces elevated levels of ammonia in plasma.

Improves protein metabolism in diseases requiring parenteral nutrition.

Pharmacokinetics

Dissociates into ornithine and aspartate, which are absorbed in the small intestine by active transport through the intestinal epithelium.

It is excreted in urine through the urea cycle.

Special instructions

If nausea or vomiting occurs, the rate of administration of the drug should be reduced.

Impact on the ability to drive vehicles and operate machinery

In case of hepatic encephalopathy, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Active ingredient

Ornithine

Composition

Active ingredient:

ornithine aspartate 3 g;

Excipients:

citric acid;

lemon and orange flavoring;

saccharin;

sodium cyclamate;

orange yellow (E110);

PVP;

levulose

Pregnancy

During pregnancy, the use of the drug is possible only under the strict supervision of a doctor.

Breastfeeding should be stopped during treatment.

Contraindications

Severe renal impairment (plasma creatinine level 3 mg/100 ml).

Side Effects

Rarely – skin reactions, in some cases – nausea, vomiting.

Overdose

Symptoms: increased severity of side effects.

Storage conditions

At a temperature not exceeding 25 °C.

Shelf life

3 years

Manufacturer

Kloke Pharma-Service GmbH, Germany