Grammidine, spray 0.06mg+0.1mg/dose 112 doses
€12.76 €10.64
Combination drug for the treatment of infectious and inflammatory diseases of the throat and oral cavity.
The drug contains the antimicrobial agent Gramicidin C and the antiseptic agent – cetylpyridinium chloride. The mechanism of action of Gramicidin C is connected with increase of permeability of the cytoplasmic membrane of the microbial cell, which breaks its resistance and causes its death.
Gramicidin C has antibacterial action against a wide range of Gram-positive and Gram-negative microorganisms. Cetylpyridinium chloride refers to antiseptic agents, suppresses the growth and reproduction of pathogens of infectious diseases of the mouth and throat. The drug has an antimicrobial effect, reduces inflammation, soothes discomfort in the throat and facilitates swallowing.
Pharmacokinetics
Topical action drug. According to preclinical pharmacokinetic studies there is practically no absorption.
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Indications
Gum inflammation, Laryngitis, Respiratory tract infections, Pharyngitis, Sore throat, Cough, Angina, Periodontitis, TonsillitisInfectious and inflammatory diseases of the mouth and throat: pharyngitis, tonsillitis, periodontitis, gingivitis, stomatitis.
Composition
One dose of the drug contains:
Active ingredients:
- Gramicidin C dihydrochloride – 0.0638 mg (in terms of Gramicidin C – 0.06 mg)
- Cetylpyridinium chloride – 0.10 mg
Excipients:
- Ethanol 96% – 19.00 mg
- Succralose – 0.20 mg
- Glycerol – 33.20 mg
- Mint flavoring – 0.82 mg
- Citric acid monohydrate – 0.058 mg
- Pharmonic acid – 0.058 mg
- Sodium citrate – 0.00 mgSodium citrate – 0.022 mg
- Polysorbate 80 – 0.40 mg
- Methyl parahydroxybenzoate (methyl paraben) – 0.184 mg
- Polypropylene 80 – 0.05 mg
- MethylHydroxybenzoate (methyl paraben).
- Propylparahydroxybenzoate (propylparaben) – 0.02 mg
- Purified water – up to 0.2 ml.
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How to take, the dosage
Topically, by spraying on the mucous membrane of the mouth and throat. It is used after meals.
Dosage for adults: 4 injections per application, 3 times a day for 7 days. Immediately after using the drug, you should refrain from eating or drinking for 1 hour.
If after treatment, there is no improvement or if symptoms worsen or new symptoms develop, you should consult a physician.
To use the drug only according to the indication, route of administration, and dosage listed in the directions.
Interaction
At the present time, no cases of clinically significant interactions with other drugs have been described.
Special Instructions
Do not use the drug in the presence of open wounds in the oral cavity, as cetylpyridinium chloride slows wound healing. The drug contains ethanol. The maximum single dose of the drug contains up to 0.08 g of ethanol.
Synopsis
Transparent or opalescent colorless or yellowish solution with a characteristic odor of mint.
Contraindications
-High sensitivity to Gramicidin C, Cetylpyridinium Chloride and other components of the drug;
-Pregnancy (1st trimester);
– Breast-feeding period;
-children under 6 years of age.
Side effects
Allergic reactions to components of the drug are possible.
If you experience or worsen the side effects mentioned in the instructions, or if you notice any other side effects not mentioned in the instructions, tell your doctor.
Pregnancy use
Pregnancy (II-III trimester). Consult a physician before using the drug if you are pregnant or if you suspect that you might be pregnant or are planning to become pregnant. Adequate controlled studies of the drug use in pregnancy have not been conducted. Use of the drug in the first trimester of pregnancy is contraindicated. Administration of the drug in the II-III trimesters of pregnancy is possible if the potential benefit to the mother exceeds the possible risk to the fetus. There are no data on penetration of the drug components into breast milk. If it is necessary to use the drug during lactation, breastfeeding should be stopped.
Weight | 0.200 kg |
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Shelf life | 2 years. Do not use after the expiration date printed on the package. |
Conditions of storage | In the original package at a temperature not exceeding 25 ° C. Store out of the reach of children. |
Manufacturer | Famar Netherlands B.V., Netherlands |
Medication form | topical spray |
Brand | Famar Netherlands B.V. |
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