Gliatilin, 400 mg capsules 56 pcs

Name: Gliatilin, 400 mg capsules 56 pcs
SKU: 511218
Availability: InStock

€59.33

EAN: 4603569000045 SKU: 511218 Categories: Brain Enhancements, Medicine, Neurology and Psychiatry

Description

Pharmacotherapeutic group: nootropic medicine

ATX code:

Pharmacological Properties

Pharmacodynamics

Gliatilin is choline alphoscerate, which is a cholinomimetic of central action with predominant effect on the central nervous system.

The drug contains 40.5 % of choline which is released from the compound in the brain; choline participates in the biosynthesis of acetylcholine (one of the main mediators of nerve excitation). Alphoscerate is biotransformed to glycerophosphate, which is a precursor of phospholipids.

Acetylcholine has a positive effect on nerve impulse transmission, and glycerophosphate participates in the synthesis of phosphatidylcholine (membrane phospholipid), as a result improving membrane elasticity and receptor function.

Gliatylin increases metabolic processes and activates the structures of the reticular formation of the brain.

It has a preventive and corrective effect on factors of involutional psychoorganic syndrome, such as changes in the phospholipid composition of neuronal membranes and decreased cholinergic activity.

Pharmacodynamic studies have shown that Gliatilin acts on synaptic, including cholinergic transmission of nerve impulse (neurotransmission), neuronal membrane plasticity and receptor function.

Pharmacokinetics

Absorption when ingested is 88%; easily penetrates the blood-brain barrier, accumulates mainly in the brain (concentration in the brain reaches 45% of blood levels), lungs and liver; 85% is excreted by the lungs as carbon dioxide, the remaining amount (15%) is excreted by the kidneys and through the intestine.

It does not affect the reproductive cycle, has no teratogenic and mutagenic effects.

Indications
Indications
Cerebral circulation disorders of ischemic type (acute and recovery periods) and hemorrhagic type (recovery period).
Psychoorganic syndrome against involutionary and degenerative processes of the brain.
Consequences of cerebrovascular insufficiency or primary and secondary cognitive disorders in the elderly, characterized by memory impairment, confusion, disorientation, decreased motivation and initiative, decreased concentration.
Disorders of behavior and affective sphere in old age: emotional lability, increased irritability, decreased interest; senile pseudo-melancholy.
Multi-infarct dementia.
.

Active ingredient
Active ingredient
Choline alphoscerate

Composition
Composition
One capsule contains:
Active ingredient: choline alphoscerate 400.0 mg.
Associates: glycerol, purified water. Capsule shell composition: gelatin, esitol, sorbitanes,
Sodium ethyl parahydroxybenzoate, sodium propyl parahydroxybenzoate, titanium dioxide (E171), iron oxide dye (E172).

How to take, the dosage
How to take, the dosage
Capsules are taken orally before a meal with water. 1 capsule (400 mg) 2-3 times a day. The doctor determines the duration of treatment individually, depending on the clinical picture and characteristics of the course of the disease, age and tolerance of the drug.

Interaction
Interaction
Clinically significant interaction of the drug with other drugs has not been established.

Special Instructions
Special Instructions
Nausea may result from dopaminergic activation.
Efficacy and safety in children under 18 years of age have not been established.
Effects on the ability to drive vehicles
Vehicles and vehicles
. During treatment, caution should be exercised when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and quick psychomotor reactions.

Synopsis
Synopsis
Oval, yellow, opaque, soft gelatin capsules containing a viscous, colorless solution.

Contraindications
Contraindications
High sensitivity to the ingredients.
Pregnancy.
Breast-feeding period.
Children under 18 years of age (due to lack of data).

Side effects
Side effects
Digestive system: nausea (which is mainly due to secondary dopaminergic activation), abdominal pain. Nervous system disorders: short-term confusion (in this case the drug dose should be reduced). The drug is well tolerated even with long-term use.

Overdose
Overdose
Symptoms: nausea. Possible increase in the severity of dose-dependent side effects. Treatment: symptomatic therapy. The effectiveness of dialysis has not been established.

Pregnancy use
Pregnancy use
The use of Gliatilin during pregnancy and breastfeeding is contraindicated.

Similarities
Similarities
Gliatilin, Cerepro, Cereton, Holitilin, Noocholin Rompharma, Choline alphoscerate

Additional information
Weight 0.070 kg
Shelf life
3 years.
Conditions of storage
At a temperature not exceeding 25°C. Keep out of reach of children.
Manufacturer
Catalent Italia S.P.A., Italy
Medication form
capsules
Brand
Catalent Italia S.P.A.