Folacin, tablets 5 mg 30 pcs

Folacin is a B vitamin. In the body it is converted to tetrahydrofolic acid as a coenzyme involved in various metabolic processes and necessary for normal maturation of megaloblasts and formation of normoblasts. When folic acid deficiency develops megaloblastic type of hematopoiesis. It stimulates erythropoiesis, participates in the synthesis of amino acids (including methionine, serine, glycine), nucleic acids, purines, pyrimidines, and in the metabolism of choline and histidine. During pregnancy, performs a protective function against the action of teratogenic and fetal damaging factors. Contributes to normal maturation and functioning of the placenta.

Pharmacokinetics

After oral administration, folic acid is absorbed in the gastrointestinal tract and is almost completely bound to plasma proteins. It is deposited and metabolized in the liver with the formation of tetrahydrofolic acid (in the presence of ascorbic acid under the action of the enzyme dihydrofolate reductase).

It penetrates through the HEB, the placenta and into the breast milk. T_max in blood is 30-60 minutes. It is excreted by the kidneys both unchanged (if the dose taken significantly exceeds the daily requirement) and as metabolites. Excreted by hemodialysis. 5 mg of folic acid taken orally is eliminated from the body in 5 hours.

Form of release

Pills